Jan Christoph Koch

Universitätsmedizin Göttingen — Germany

Medicine · Health Sciences

44h-index17.6kcitations135works9.32yr avg
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Research Topics

Amyotrophic Lateral Sclerosis Research(47), Neurogenetic and Muscular Disorders Research(42), Nerve injury and regeneration(22), Parkinson's Disease Mechanisms and Treatments(21), RNA modifications and cancer(17)

Publications128 total

EARLY-ALS: A Multicentre Study on Presymptomatic and Prodromal Amyotrophic Lateral Sclerosis
2026Open Access
Compound Muscle Action Potential (CMAP) Amplitude Trajectories and Pattern in Adults with 5q‐Spinal Muscular Atrophy Receiving Nusinersen Therapy: A Multicenter, Binational Observational Study
European Journal of Neurology·2025· 3 citedOpen Access
Phenotypic intrafamilial variability of 5q-associated spinal muscular atrophy: A systematic multicentre sibling study
Journal of Neuromuscular Diseases·2025· 1 citedOpen Access
Respiratory function in 192 adult patients with spinal muscular atrophy (SMA) treated with nusinersen – a multicenter observational study
Orphanet Journal of Rare Diseases·2025· 1 citedOpen Access
Fasudil attenuates disease spreading in ALS – a post-hoc analysis of the ROCK-ALS trial
2025Open Access
Retrograde axonal transport of autophagic vesicles and dynein-dynactin protein interaction are attenuated during aging in the rat optic nerve in vivo
Neural Regeneration Research·2025Open Access
Die Selbstbewertung der Funktionsskala für Amyotrophe Lateralsklerose (ALSFRS-R) per Smartphone der Patienten ist gegenüber der klinischen Datenerfassung nicht unterlegen
Nervenheilkunde·2025Open Access
Erste Daten zum DGM-geförderten Projekt „Defizite und Verbesserungspotential in der psychosozialen und palliativen Versorgung von ALS-Patient:innen in Deutschland“
Nervenheilkunde·2025Open Access
Provision, cough efficacy and treatment satisfaction of mechanical insufflation-exsufflation in a large multicenter cohort of patients with amyotrophic lateral sclerosis
Scientific Reports·2025· 1 citedOpen Access
Self-assessment of amyotrophic lateral sclerosis functional rating scale on the patient’s smartphone proves to be non-inferior to clinic data capture
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration·2025· 7 citedOpen Access
T1-relaxation times along the corticospinal tract as a diagnostic marker in patients with amyotrophic lateral sclerosis
Frontiers in Neuroimaging·2025Open Access
Long-Term Dynamics of CSF and Serum Neurofilament Light Chain in Adult Patients With 5q Spinal Muscular Atrophy Treated With Nusinersen
Neurology·2025· 9 citedOpen Access
Analysis of Conformational Molecular Changes in Cerebrospinal Fluid Using Fourier Transform Infrared Spectroscopy in Neurodegenerative Diseases
Methods in molecular biology·2025Open Access
Self-Assessment of amyotrophic lateral sclerosis functional rating scale on the patient’s smartphone proves to be non-inferior to clinic data capture
2024Open Access
Perspektiven auf das Lebensende: eine systematische Erhebung bei Patienten mit amyotropher Lateralsklerose
Der Nervenarzt·2024Open Access
Static transcranial magnetic stimulation does not alter cortical excitability in patients with amyotrophic lateral sclerosis on riluzole
Brain stimulation·2024Open Access
Safety, tolerability, and efficacy of fasudil in amyotrophic lateral sclerosis (ROCK-ALS): a phase 2, randomised, double-blind, placebo-controlled trial
The Lancet Neurology·2024· 22 citedOpen Access
Tofersen decreases neurofilament levels supporting the pathogenesis of the SOD1 p.D91A variant in amyotrophic lateral sclerosis patients
Communications Medicine·2024· 21 citedOpen Access
Patients’ and caregivers’ perception of multidimensional and palliative care in amyotrophic lateral sclerosis – protocol of a German multicentre study
Neurological Research and Practice·2024· 3 citedOpen Access
Clinical and patient‐reported outcomes and neurofilament response during tofersen treatment in <i>SOD1</i>‐related <scp>ALS</scp>—A multicenter observational study over 18 months
Muscle & Nerve·2024· 26 citedOpen Access
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Frequent Co-authors

Paul Lingor(42), Mathias Bähr(25), Lars Tönges(18), René Günther(15), Susanne Petri(14), Albert C. Ludolph(14), Andreas Hermann(12), Uwe Michel(12), Tim Hagenacker(10), Thomas Meyer(9), Julian Großkreutz(9), Isabell Cordts(8), Lars Tatenhorst(7), Ute Weyen(7), Joachim Wolf(7), Claudia D. Wurster(6), Olivia Schreiber‐Katz(6), Alma Osmanovic(6), Marcus Deschauer(6), Torsten Grehl(6)