Yutaka Hanazono

Jichi Medical University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

33h-index3.8kcitations156works0.32yr avg
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Research Topics

Virus-based gene therapy research(54), CRISPR and Genetic Engineering(41), Pluripotent Stem Cells Research(40), CAR-T cell therapy research(23), RNA Interference and Gene Delivery(22)

Publications156 total

ATM Inhibition Enhances Knock-in Efficiency by Suppressing AAV-Induced Activation of Apoptotic Pathways
Communications Biology·2026Open Access
Ataxia-Telangiectasia Mutated Inhibition Enhances Adeno-Associated Virus-Mediated Knock-in Efficiency in Pig Zygotes
2025Open Access
Transient ATM inhibition enhances knock-in efficiency and long-term engraftment of genome-edited hematopoietic stem cells
Blood·2025Open Access
3209 – ENHANCING KNOCK-IN EFFICIENCY IN HSCs BY MODULATING THE DNA DAMAGE RESPONSE VIA ATM INHIBITION
Experimental Hematology·2025
Transient ATM inhibition enhances knock-in efficiency in hematopoietic stem cells by attenuating the DNA damage response
2025· 1 citedOpen Access
Non-Invasive In Vivo Bioimaging in Pigs
International Journal of Translational Medicine·2024Open Access
In Vivo Luciferin–Luciferase Reaction in Micro-Mini Pigs Using Xenogeneic Rat Bone Marrow Transplantation
International Journal of Molecular Sciences·2024· 1 citedOpen Access
Secretory GFP reconstitution labeling of neighboring cells interrogates cell–cell interactions in metastatic niches
Nature Communications·2023· 10 citedOpen Access
PB0165 Gene Correction of Human Hemophilia B Mutation by PAM-Flexible Cas9-Mediated Base-Editing Approach
Research and Practice in Thrombosis and Haemostasis·2023Open Access
PAM-flexible Cas9-mediated base editing of a hemophilia B mutation in induced pluripotent stem cells
Communications Medicine·2023· 24 citedOpen Access
Nonviral Ex Vivo Genome Editing in Mouse Bona Fide Hematopoietic Stem Cells with CRISPR/Cas9
Methods in molecular biology·2023· 3 cited
Hormone and nuclear receptor activations are required for cardiomyocyte maturation
Journal of Molecular and Cellular Cardiology·2022
Sarcomere Shortening of Pluripotent Stem Cell-Derived Cardiomyocytes using Fluorescent-Tagged Sarcomere Proteins.
Journal of Visualized Experiments·2021
Sarcomere Shortening of Pluripotent Stem Cell-Derived Cardiomyocytes using Fluorescent-Tagged Sarcomere Proteins.
Journal of Visualized Experiments·2021· 2 cited
Non-viral ex vivo genome-editing in mouse bona fide hematopoietic stem cells with CRISPR/Cas9
Molecular Therapy — Methods & Clinical Development·2021· 12 citedOpen Access
Fetal sheep support the development of hematopoietic cells in vivo from human induced pluripotent stem cells
Experimental Hematology·2021· 3 citedOpen Access
Generation of Efficient Knock-in Mouse and Human Pluripotent Stem Cells Using CRISPR-Cas9
Methods in molecular biology·2021· 3 cited
A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation
Scientific Reports·2020· 33 citedOpen Access
Generation of novel <i>Il2rg</i>-knockout mice with clustered regularly interspaced short palindromic repeats (CRISPR) and Cas9
EXPERIMENTAL ANIMALS·2019· 6 citedOpen Access
Lysine-specific demethylase 1 inhibitors prevent teratoma development from human induced pluripotent stem cells
Oncotarget·2018· 16 citedOpen Access
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Frequent Co-authors

Keiya Ozawa(16), Hiroaki Mizukami(13), Akihiro Kume(13), Takashi Okada(12), Shin‐ichi Muramatsu(9), Hiroaki Shibata(9), Takashi Matsushita(8), Cynthia E. Dunbar(8), Yasuji Ueda(7), K Ozawa(5), Kazuaki Nakano(5), Masahito Watanabe(5), Tomoyuki Abe(5), Hiroshi Nagashima(5), Naohide Ageyama(5), Keiji Terao(5), Lijun Wang(4), Yanyan Lu(4), Imaharu Nakano(4), Stephanie Sellers(4)