T. Harma C. Brondijk

University of Applied Sciences Utrecht — Netherlands

Medicine · Health Sciences

17h-index1.3kcitations24works0.02yr avg
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Research Topics

Platelet Disorders and Treatments(5), Cell Adhesion Molecules Research(5), Enzyme Structure and Function(5), Immune Response and Inflammation(3), Amino Acid Enzymes and Metabolism(3)

Publications24 total

Structural insights into C3 convertase activity of the classical pathway of complement
Nature Communications·2025Open Access
Structural insights into C3 convertase activity of the classical pathway of complement
2025Open Access
Structural insights into collagen binding by platelet receptor glycoprotein VI
Blood·2022· 45 citedOpen Access
Insights Into Enhanced Complement Activation by Structures of Properdin and Its Complex With the C-Terminal Domain of C3b
Frontiers in Immunology·2019· 42 citedOpen Access
Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3)
Proceedings of the National Academy of Sciences·2015· 97 citedOpen Access
When less becomes more: Optimization of protein expression in HEK293–EBNA1 cells using plasmid titration – A case study for NLRs
Protein Expression and Purification·2014· 17 cited
TLR Accessory Molecule RP105 (CD180) Is Involved in Post-Interventional Vascular Remodeling and Soluble RP105 Modulates Neointima Formation
PLoS ONE·2013· 34 citedOpen Access
Formation and Structure of a NAIP5-NLRC4 Inflammasome Induced by Direct Interactions with Conserved N- and C-terminal Regions of Flagellin
Journal of Biological Chemistry·2012· 155 citedOpen Access
Evasion of Toll-like receptor 2 activation by staphylococcal superantigen-like protein 3
Journal of Molecular Medicine·2012· 96 cited
Implications for collagen I chain registry from the structure of the collagen von Willebrand factor A3 domain complex
Proceedings of the National Academy of Sciences·2012· 80 citedOpen Access
Crystal structure of the von Willebrand factor A3 domain in complex with a collagen III derived triple-helical peptide
2012
Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI
Blood·2009· 77 citedOpen Access
Crystal structures of TAFI elucidate the inactivation mechanism of activated TAFI: a novel mechanism for enzyme autoregulation
Blood·2008· 87 citedOpen Access
Substitution of Tyrosine 146 in the dI Component of Proton-translocating Transhydrogenase Leads to Reversible Dissociation of the Active Dimer into Inactive Monomers
Journal of Biological Chemistry·2007· 6 citedOpen Access
Kinetic and Mutational Analyses of the Major Cytosolic Exopolyphosphatase from Saccharomyces cerevisiae
Journal of Biological Chemistry·2007· 27 citedOpen Access
The NapF protein of the Escherichia coli periplasmic nitrate reductase system: demonstration of a cytoplasmic location and interaction with the catalytic subunit, NapA
Microbiology·2006· 49 cited
The Role of Invariant Amino Acid Residues at the Hydride Transfer Site of Proton-translocating Transhydrogenase
Journal of Biological Chemistry·2006· 14 citedOpen Access
Structure of Transhydrogenase (dI.S138A.NADH)2(dIII.NADPH)1 asymmetric complex
2006
NapGH components of the periplasmic nitrate reductase of Escherichia coli K-12: location, topology and physiological roles in quinol oxidation and redox balancing
Biochemical Journal·2004· 85 citedOpen Access
Roles of NapF, NapG and NapH, subunits of the Escherichia coli periplasmic nitrate reductase, in ubiquinol oxidation
Molecular Microbiology·2002· 337 citedOpen Access
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Frequent Co-authors

Eric G. Huizinga(10), Scott A. White(4), David J. Richardson(3), Jeffrey A. Cole(3), Marian Versteeg(3), Richard W. Farndale(3), Piet Gros(3), Els F. Halff(2), L.J. Feitsma(2), Carla J. C. de Haas(2), Jos A. G. van Strijp(2), Arjaree Nilavongse(2), Dominique Bihan(2), Bert Poolman(2), Wil N. Konings(2), Roger Durand(2), Mark van der Giezen(2), Jan C. Gottschal(2), R. A. Prins(2), M. Fèvre(2)