E. O. Stapley

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Medicine · Health Sciences

25h-index6.3kcitations56works0.02yr avg
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Research Topics

Microbial Natural Products and Biosynthesis(16), Antibiotics Pharmacokinetics and Efficacy(15), Phenothiazines and Benzothiazines Synthesis and Activities(11), Antibiotic Resistance in Bacteria(9), Synthesis of β-Lactam Compounds(6)

Publications55 total

The Discovery of Cell Wall Active Antibacterial Antibiotics
Critical Reviews in Biotechnology·1992· 40 cited
Isolation and Characterization of the Producing Organism
1989· 33 cited
Difficidin and oxydifficidin: Novel broad spectrum antibacterial antibiotics produced by Bacillus subtilis. I.Production, taxonomy and antibacterial activity.
The Journal of Antibiotics·1987· 120 citedOpen Access
A potent nonpeptide cholecystokinin antagonist selective for peripheral tissues isolated from Aspergillus alliaceus
Science·1985· 320 cited
Use of a computer to group actinomycetes for studies on the ecology of soil microorganisms
Applied and Environmental Microbiology·1984· 3 citedOpen Access
Studies on the ecology of West Australian actinomycetes: Factors which influence the diversity and types of actionomycetes in Australian soils
Microbial Ecology·1984· 9 cited
Discovery, production and purification of the Na+,K+ activated ATPase inhibitor, L-681,110 from the fermentation broth of Streptomyces sp. MA-5038.
The Journal of Antibiotics·1984· 24 citedOpen Access
ChemInform Abstract: IVERMECTIN: A POTENT NEW ANTIPARASITIC AGENT
Chemischer Informationsdienst·1983
GELRITE as an Agar Substitute in Bacteriological Media
Applied and Environmental Microbiology·1983· 103 citedOpen Access
Ivermectin: A Potent New Antiparasitic Agent
Science·1983· 815 cited
Quaternary hetero cyclylamino beta lactams 4. comparison of the in vivo anti bacterial activities of l 640876 mecillinam cefoxitin and cefotaxime
1983
Ivermectin: a potent new antiparasitic agent [Nematode and arthropod parasites].
1983
Quaternary heterocyclylamino .BETA.-lactams. IV. Comparison of the in vivo antibacterial activities of L-640,876, mecillinam, cefoxitin and cefotaxime.
The Journal of Antibiotics·1983· 1 citedOpen Access
Screening for New β-Lactam Antibiotics
Handbook of experimental pharmacology·1983· 2 cited
Avermectins, antiparasitic lactones produced by Streptomyces avermitilis isolated from a soil in Japan.
1982· 18 cited
Epithienamycins. II. Isolation and structure assignment.
The Journal of Antibiotics·1981· 49 citedOpen Access
STUDIES ON THE AVERMECTIN FERMENTATION
Elsevier eBooks·1981· 4 cited
Epithienamycins-novel .BETA.-lactams related to thienamycin I. Production and antibacterial activity.
The Journal of Antibiotics·1981· 45 citedOpen Access
An animal model for assessing pain-on-injection of antibiotics
Journal of Pharmacological Methods·1980· 20 cited
Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.
Proceedings of the National Academy of Sciences·1980· 1.6k citedOpen Access
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Frequent Co-authors

David Hendlin(15), A. Kathrine Miller(15), H. B. Woodruff(11), S. B. Zimmerman(10), Jerome Birnbaum(8), Barbara A. Pelak(8), E. Celozzi(8), Richard L. Monaghan(7), H. Wallick(7), Sebastian Hernandez(7), J.M. Mata(6), Eugene L. Dulaney(6), G. Albers‐Schönberg(5), Sara Currie(5), M. Jackson(5), Thomas W. Miller(5), S. Mochales(5), Otto D. Hensens(3), Richard W. Burg(3), Yu-Lin Kong(3)