Takaaki Akaike

Tohoku University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

79h-index22.3kcitations517works5.52yr avg
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Research Topics

Sulfur Compounds in Biology(168), Nitric Oxide and Endothelin Effects(113), Redox biology and oxidative stress(55), Genomics, phytochemicals, and oxidative stress(38), Adenosine and Purinergic Signaling(27)

Publications517 total

Mitochondria regulate the cell fate decisions of megakaryocyte-erythroid progenitors
Stem Cell Reports·2025Open Access
Author response: Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein
2025Open Access
Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein
eLife·2025· 3 citedOpen Access
Dynamic transformation of the sulfur metabolome during natto fermentation: Supersulfide omics study
Nitric Oxide·2025
The Supersulfide-Producing Activity of Rat Cystathionine γ-Lyase Is Irreversibly Inactivated by L-CysNO but Not by L-GSNO
Antioxidants·2025· 1 citedOpen Access
Sex-dependent epigenetic disruption of YY1 binding by prenatal BPA exposure downregulates Matr3 and alters Agap1 splicing in the offspring hippocampus
Biology of Sex Differences·2025· 1 citedOpen Access
[Sulfur Metabolism in Cancer Malignancy and Its Potential for Therapeutic Application].
PubMed·2025
The Supersulfide-Producing Activity of Cystathionine γ-Lyase Is Irreversiblely Inactivated by L-CysNO but Not by L-GSNO
Preprints.org·2025Open Access
A novel pathway for supersulfides production catalyzed by NOX and NOS
Free Radical Biology and Medicine·2025
The persulfide and polysulfide puzzle: Novel tools and methods to assemble the pieces
Free Radical Biology and Medicine·2025
Physiological formation and function of supersulfides, cyclo-octasulfur (S8) in adipocyte
Free Radical Biology and Medicine·2025
Sulfide quinone oxidoreductase (SQR)-mediated cross-species mitochondrial sulfur respiration by supersulfides
Free Radical Biology and Medicine·2025
Supersulfides protect against SARS-CoV-2 infection by targeting viral thiol proteases and spike proteins
Free Radical Biology and Medicine·2025
Oxygen needs sulfur, sulfur needs oxygen: a relationship of interdependence
The EMBO Journal·2025· 6 citedOpen Access
Author response: Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein
2025Open Access
Growth inhibitory factor/metallothionein-3 is a sulfane sulfur-binding protein
2025Open Access
Supersulfide donors and their therapeutic targets in inflammatory diseases
Frontiers in Immunology·2025· 5 citedOpen Access
Supersulfide controls intestinal inflammation by suppressing CD4+ T cell proliferation
Frontiers in Immunology·2025· 2 citedOpen Access
Supersulfides contribute to joint homeostasis and bone regeneration
Osteoarthritis and Cartilage·2025
Mitochondrial translation regulates terminal erythroid differentiation by maintaining iron homeostasis
Science Advances·2025· 1 citedOpen Access
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Frequent Co-authors

Hiroshi Maeda(20), Tomohiro Sawa(19), Yoshito Kumagai(7), Hiroshi Maeda(7), Tatsuya Okamoto(7), Tomoaki Ida(6), Hideshi Ihara(6), Hozumi Motohashi(6), Jun Fang(6), Shigemoto Fujii(5), Masayuki Yamamoto(5), Jon M. Fukuto(5), Tetsuro Matsunaga(4), Ming Xian(4), Motohiro Nishida(4), Péter Nagy(4), Yoichi Miyamoto(4), Katsuhiko Ono(3), Jun Wu(3), Teruo Akuta(3)