Jingen Zhu

University of America — United States

Environmental Science · Physical Sciences

17h-index1.2kcitations35works1.42yr avg
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Research Topics

Bacteriophages and microbial interactions(27), Monoclonal and Polyclonal Antibodies Research(15), CRISPR and Genetic Engineering(8), SARS-CoV-2 and COVID-19 Research(7), vaccines and immunoinformatics approaches(5)

Publications35 total

In situ structures of the portal-neck-tail complex of bacteriophage T4 inform a viral genome positioning mechanism
Nature Communications·2026Open Access
Cryo-EM structures of bacteriophage T4 portal-neck assembly intermediates reveal a viral genome retention mechanism
Nature Communications·2026· 1 citedOpen Access
Targeted Delivery of Nucleic Acid and Protein Cargos into Primary Human Hematopoietic Stem Cells Using Bacteriophage T4
2026
Targeted bacteriophage T4 nanoparticles reverse HIV-1 latency in human T cell line models
iScience·2025· 1 citedOpen Access
A Modular Bacteriophage T4 Nanoparticle Platform Enables Rapid Design of Dual COVID‐19‐Flu Mucosal Vaccines
Small Science·2025Open Access
A Modular Bacteriophage T4 Nanoparticle Platform Enables Rapid Design of Dual COVID‐19‐Flu Mucosal Vaccines
Small Science·2025· 1 citedOpen Access
A Modular Bacteriophage T4 Nanoparticle Platform Enables Rapid Design of Dual COVID-19-Flu Mucosal Vaccines
2024Open Access
Bacteriophage T4 as a Protein-Based, Adjuvant- and Needle-Free, Mucosal Pandemic Vaccine Design Platform
Annual Review of Virology·2024· 8 citedOpen Access
T4 bacteriophage nanoparticles engineered through CRISPR provide a versatile platform for rapid development of flu mucosal vaccines
Antiviral Research·2023· 12 cited
Design of bacteriophage T4-based artificial viral vectors for human genome remodeling
Nature Communications·2023· 41 citedOpen Access
Understanding Bacteriophage Tail Fiber Interaction with Host Surface Receptor: The Key “Blueprint” for Reprogramming Phage Host Range
International Journal of Molecular Sciences·2022· 165 citedOpen Access
Bacteriophage T4 as a nanovehicle for delivery of genes and therapeutics into human cells
Current Opinion in Virology·2022· 19 citedOpen Access
A Bacteriophage-Based, Highly Efficacious, Needle- and Adjuvant-Free, Mucosal COVID-19 Vaccine
mBio·2022· 31 citedOpen Access
Rapid Development of a Mucosal Nanoparticle Flu Vaccine by Genetic Engineering of Bacteriophage T4 using CRISPR-Cas
2022· 1 citedOpen Access
A bacteriophage-based, highly efficacious, needle and adjuvant-free, mucosal COVID-19 vaccine
2022· 3 citedOpen Access
CRISPR Engineering of Bacteriophage T4 to Design Vaccines Against SARS-CoV-2 and Emerging Pathogens
Methods in molecular biology·2021· 12 citedOpen Access
Engineering T4 Bacteriophage for <i>In Vivo</i> Display by Type V CRISPR-Cas Genome Editing
ACS Synthetic Biology·2021· 39 cited
A universal bacteriophage T4 nanoparticle platform to design multiplex SARS-CoV-2 vaccine candidates by CRISPR engineering
Science Advances·2021· 67 citedOpen Access
A phage-encoded nucleoid associated protein compacts both host and phage DNA and derepresses H-NS silencing
Nucleic Acids Research·2021· 14 citedOpen Access
Targeted Bacteriophage T4 Nanoparticles Reverse HIV-1 Latency in CD4+ Human T Cells
2021· 7 citedOpen Access
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Frequent Co-authors

Venigalla B. Rao(25), Himanshu Batra(13), Xiaorong Wu(13), Tao Pan(12), Ashok K. Chopra(11), Swati Jain(10), Marthandan Mahalingam(9), Jian Sha(9), Neeti Ananthaswamy(8), Paul B. Kilgore(8), Pan Tao(6), Dong Qian(5), Lizhe An(5), Yun Xiang(5), Aleksandra Drelich(4), Chien‐Te K. Tseng(4), Cen Chen(4), Emily K. Hendrix(4), Weichun Tang(3), Qiong Nan(3)