Michelle Clements

MRC Clinical Trials Unit at UCL — United Kingdom

Immunology and Microbiology · Life Sciences

19h-index2.4kcitations47works7.32yr avg
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Research Topics

Parasites and Host Interactions(10), Global Maternal and Child Health(8), Statistical Methods in Clinical Trials(8), Wildlife Ecology and Conservation(5), Pneumonia and Respiratory Infections(5)

Publications46 total

A rapid time-resolved host gene expression signature predicts responses to antibiotic treatment in neonatal bacterial sepsis
Science Translational Medicine·2025Open Access
Safety and efficacy of antiseptic cleansing to reduce vertical transmission of multi-drug resistant pathogens to neonates (NeoVT-AMR)
2025Open Access
A Bayesian framework to evaluate non-inferiority in randomized controlled trials of uncommon conditions
Journal of Clinical Epidemiology·2025Open Access
Exploring different objectives in non-inferiority trials
BMJ·2024· 12 citedOpen Access
High-resolution genomics identifies pneumococcal diversity and persistence of vaccine types in children with community-acquired pneumonia in the UK and Ireland
BMC Microbiology·2024· 7 citedOpen Access
System-wide approaches to antimicrobial therapy and antimicrobial resistance in the UK: the AMR-X framework
The Lancet Microbe·2024· 16 citedOpen Access
Safety and efficacy of whole-body chlorhexidine gluconate cleansing with or without emollient in hospitalised neonates (NeoCHG): a multicentre, randomised, open-label, factorial pilot trial
EClinicalMedicine·2024· 10 citedOpen Access
Incidence, pathogens and antimicrobial resistance of blood and cerebrospinal fluid isolates from a tertiary neonatal unit in South Africa: A 10 year retrospective review
PLoS ONE·2024· 13 citedOpen Access
PA-675 Navigating the COVID-19 pandemic for participant recruitment and follow-up: experiences from the PediCAP clinical trial consortium
2023Open Access
Practical approaches to Bayesian sample size determination in non‐inferiority trials with binary outcomes
Statistics in Medicine·2023· 6 citedOpen Access
Improving Clinical Trial Interpretation with ACCEPT Analyses
NEJM Evidence·2022· 12 citedOpen Access
Improving clinical trial interpretation with ACCEPT analyses
arXiv (Cornell University)·2022Open Access
Improving clinical trial interpretation with Acceptability Curve Estimation (ACE)
UCL Discovery (University College London)·2022
Incidence and All-Cause Mortality Rates in Neonates Infected With Carbapenem Resistant Organisms
Frontiers in Tropical Diseases·2022· 18 citedOpen Access
Optimised versus standard dosing of vancomycin in infants with Gram-positive sepsis (NeoVanc): a multicentre, randomised, open-label, phase 2b, non-inferiority trial
The Lancet Child & Adolescent Health·2021· 23 citedOpen Access
Effectiveness of a Fortified Drink in Improving B Vitamin Biomarkers in Older Adults: A Controlled Intervention Trial
Research Square (Research Square)·2021Open Access
Global antibiotic dosing strategies in hospitalised children: Characterising variation and implications for harmonisation of international guidelines
PLoS ONE·2021· 6 citedOpen Access
Variation in Target Attainment of Beta‐Lactam Antibiotic Dosing Between International Pediatric Formularies
Clinical Pharmacology & Therapeutics·2021· 8 citedOpen Access
Constructing a representative in‐silico population for paediatric simulations: Application to HIV‐positive African children
British Journal of Clinical Pharmacology·2020· 24 citedOpen Access
Impact of atrophic gastritis on vitamin B12 biomarkers and bone mineral density in older adults from the TUDA study
2020
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Frequent Co-authors

Mike Sharland(12), A. Sarah Walker(9), Matteo Quartagno(9), Loeske E. B. Kruuk(7), Julia Bielicki(7), Giuseppina Ortu(6), Carl H. Campbell(6), Daniel G. Colley(6), Alan Fenwick(6), Conor Tweed(6), Ian R. White(6), Josephine M. Pemberton(5), Tim Clutton‐Brock(5), Charles H. King(5), Fiona Fleming(5), Rebecca Turner(5), David Dunn(5), Victoria Cornelius(5), Suzie Cro(5), Daniel H. Nussey(4)