Tommy Szeto

University of Arizona — United States

Medicine · Health Sciences

8h-index1.5kcitations8works0.02yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(8), Computational Drug Discovery Methods(6), Calpain Protease Function and Regulation(3), interferon and immune responses(2), Protein Structure and Dynamics(1)

Publications8 total

Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay
ACS Central Science·2021· 192 citedOpen Access
Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir
ACS Pharmacology & Translational Science·2021· 96 citedOpen Access
Expedited Approach toward the Rational Design of Noncovalent SARS-CoV-2 Main Protease Inhibitors
Journal of Medicinal Chemistry·2021· 157 citedOpen Access
Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and FlipGFP-based reporter assay
2021· 8 citedOpen Access
Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses
ACS Infectious Diseases·2021· 115 citedOpen Access
Boceprevir, calpain inhibitors II and XII, and GC-376 have broad-spectrum antiviral activity against coronaviruses in cell culture
2020· 15 citedOpen Access
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
Cell Research·2020· 870 citedOpen Access
Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease
2020· 92 citedOpen Access

Frequent Co-authors

Chunlong Ma(8), Yanmei Hu(8), Jun Wang(8), M. Sacco(6), Yu Chen(6), Julia A. Townsend(5), Michael T. Marty(5), Brett L. Hurst(4), Xiujun Zhang(4), E. Bart Tarbet(4), Xiangzhi Meng(4), Fushun Zhang(4), Yan Xiang(4), Zilei Xia(3), Mandy Ba(3), Naoya Kitamura(2), George Lambrinidis(1), Maura V. Gongora(1), Antonios Kolocouris(1), Xiujun Zhang(1)