José A. Santiago-Rivera

Virginia Tech — United States

Medicine · Health Sciences

3h-index52citations5works0.02yr avg
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Research Topics

Adipose Tissue and Metabolism(3), Computational Drug Discovery Methods(2), Receptor Mechanisms and Signaling(2), Circadian rhythm and melatonin(1), Liver Disease Diagnosis and Treatment(1)

Publications5 total

<b>Liver-selective imidazolopyrazine mitochondrial uncoupler SHD865 reverses adiposity and glucose intolerance in mice</b>
2023Open Access
<b>Liver-selective imidazolopyrazine mitochondrial uncoupler SHD865 reverses adiposity and glucose intolerance in mice</b>
2023Open Access
Liver-Selective Imidazolopyrazine Mitochondrial Uncoupler SHD865 Reverses Adiposity and Glucose Intolerance in Mice
Diabetes·2023· 9 citedOpen Access
Conversion of oxadiazolo[3,4-b]pyrazines to imidazo[4,5-b]pyrazines via a tandem reduction-cyclization sequence generates new mitochondrial uncouplers
Bioorganic & Medicinal Chemistry Letters·2022· 6 citedOpen Access
[1,2,5]Oxadiazolo[3,4-<i>b</i>]pyrazine-5,6-diamine Derivatives as Mitochondrial Uncouplers for the Potential Treatment of Nonalcoholic Steatohepatitis
Journal of Medicinal Chemistry·2020· 37 citedOpen Access

Frequent Co-authors

Stefan R. Hargett(5), Yumin Dai(5), Kyle L. Hoehn(5), Webster L. Santos(5), Stephanie J. Alexopoulos(4), Sing-Young Chen(4), Divya P. Shah(4), Simon P. Tucker(4), Martina Beretta(3), Ellen M. Olzomer(3), Ashleigh M. Philp(3), Keyong Li(3), Catherine Li(3), Thurl E. Harris(3), Brendan Lee(3), Michel Wathier(3), J Cermák(3), Nigel Turner(3), Douglas A. Bayliss(3), Andrew Philp(3)