Guy Bormans

Pharmac — New Zealand

Medicine · Health Sciences

72h-index19.1kcitations641works1.82yr avg
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Research Topics

Medical Imaging Techniques and Applications(153), Radiopharmaceutical Chemistry and Applications(133), Neuroscience and Neuropharmacology Research(67), Cannabis and Cannabinoid Research(56), Medical Imaging and Pathology Studies(35)

Publications637 total

Radiosynthesis and first in vitro evaluation of [11C]Onalespib for Hsp90 cancer imaging
Nuclear Medicine and Biology·2025Open Access
Affinity Tuning of Albumin-Binding VHH Constructs to Modulate Blood Circulation for Optimized Radiopharmaceutical Performance
Nuclear Medicine and Biology·2025Open Access
Preclinical evaluation of [11C]HSP990 for in vivo visualization of Hsp90 in cryptococcal infection
Nuclear Medicine and Biology·2025
GMP compliant production of [11C]HSP990 and first-in-human whole body PET/CT imaging
Nuclear Medicine and Biology·2025
RBIO-09. Preclinical evaluation of the synergistic effect of heat shock protein 90 inhibitors with temozolomide and external beam radiotherapy in glioblastoma models
Neuro-Oncology·2025Open Access
Selective CXCR4-Targeting Antagonists Derived from LY2510924: [¹⁸F]AlF-NOTA-SC, [¹⁷⁷Lu]Lu-BL02, and [¹⁶¹Tb]Tb-BL02 as a Promising Trio for Precision Imaging and Therapy
Nuclear Medicine and Biology·2025
Evaluation of extracellular Hsp90 as a potential target for cancer PET imaging
Nuclear Medicine and Biology·2025
[11C]HSP990 PET as a translational tool to investigate the role of Hsp90 in tumours and support the development of Hsp90 therapeutics
EJNMMI Radiopharmacy and Chemistry·2025Open Access
In vivo imaging of heat shock protein 90: Diagnostic tool and support for Hsp90-targeted therapy
Cell Stress and Chaperones·2025Open Access
Dosimetry and kinetic modelling of [18F]JNJ-64511070, a novel PET ligand to quantify AMPA-associated TARP-γ8 receptors in the human brain
European Journal of Nuclear Medicine and Molecular Imaging·2025Open Access
Martinostat as a novel HDAC inhibitor to overcome tyrosine kinase inhibitor resistance in chronic myeloid leukemia
Clinical Epigenetics·2025· 1 citedOpen Access
PET imaging with [¹¹C]CHDI-00485180-R, designed as radioligand for aggregated mutant huntingtin, in people with Huntington’s disease
European Journal of Nuclear Medicine and Molecular Imaging·2025· 4 cited
Comparison of inter- and intraobserver agreement between [18F]AlF-NOTA-octreotide and [68Ga]Ga-DOTA-SSA PET/CT
EJNMMI Reports·2025· 2 citedOpen Access
In Vivo Visualization and Quantification of Brain Heat Shock Protein 90 with [<sup>11</sup>C]HSP990 in Healthy Aging and Neurodegeneration
Journal of Nuclear Medicine·2025· 4 citedOpen Access
Radiosynthesis and Evaluation of [<sup>18</sup>F]FEHSP990 as Novel PET Tracer for Hsp90 PET Imaging
Journal of Labelled Compounds and Radiopharmaceuticals·2025· 4 citedOpen Access
Indium-111-Labeled Single-Domain Antibody for <i>In Vivo</i> CXCR4 Imaging Using Single-Photon Emission Computed Tomography
Bioconjugate Chemistry·2025· 1 citedOpen Access
Development and evaluation of Hsp90-targeting nanobodies for visualisation of extracellular Hsp90 in tumours using PET imaging
EJNMMI Radiopharmacy and Chemistry·2025· 3 citedOpen Access
Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein
Fluids and Barriers of the CNS·2025· 8 citedOpen Access
Development and evaluation of deuterated [18F]JHU94620 isotopologues for the non-invasive assessment of the cannabinoid type 2 receptor in brain
EJNMMI Radiopharmacy and Chemistry·2024· 3 citedOpen Access
Selective PET imaging of CXCR4 using the Al18F-labeled antagonist LY2510924
European Journal of Nuclear Medicine and Molecular Imaging·2024· 5 citedOpen Access
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Frequent Co-authors

Koen Van Laere(17), Patrick Dupont(15), Luc Mortelmans(13), Johan Nuyts(7), Cindy Casteels(7), Luc Mortelmans(6), Patrick Flamen(6), Sigrid Stroobants(6), Alex Maes(6), Christophe M. Deroose(5), Rik Vandenberghe(5), Frederik Cleeren(5), Jan de Hoon(4), Karolien Goffin(4), Alfons Verbruggen(4), Eric Van Cutsem(3), Karin Haustermans(3), Karoline Spaepen(3), Peter Vandenberghe(3), Jan Balzarini(3)