Michael Schmueck‐Henneresse

Humboldt-Universität zu Berlin — Germany

Medicine · Health Sciences

21h-index1.6kcitations69works4.92yr avg
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Research Topics

CAR-T cell therapy research(41), Immune Cell Function and Interaction(23), T-cell and B-cell Immunology(22), CRISPR and Genetic Engineering(19), Cytomegalovirus and herpesvirus research(12)

Publications69 total

Clinical development of gene edited tacrolimus-resistant Treg (FKBP12 <sup>KO</sup> -Treg) to enable simultaneous immunosuppression and support of immune regulation
2025
An autologous human iPSC-derived 3D organoid infection model for preclinical testing of antiviral T cells
2025Open Access
HLA matching or CRISPR editing of HLA class I/II enables engraftment and effective function of allogeneic human regulatory T cell therapy in a humanized mouse transplantation model
Nature Communications·2025· 2 citedOpen Access
Multi-parametric profiling of IL-7-augmented GD2.CART products in a phase 1 clinical trial
iScience·2025Open Access
An autologous human iPSC-derived 3D organoid infection model for preclinical testing of antiviral T cells
2025Open Access
Generation of four human induced pluripotent stem cell lines from functionally distinct T cell lineages with defined or undefined T cell receptor specificity
Stem Cell Research·2025Open Access
Effects of CRISPR-Cas9-mediated FOXP3 knockout on CAR T cell potency
Molecular Therapy — Methods & Clinical Development·2025· 1 citedOpen Access
Generation of Regulatory T Cells From Human Memory CD4 <sup>+</sup> T Cells by Upregulation of Naked Cuticle Homolog 2
European Journal of Immunology·2025Open Access
POS0722 CHEMOKINE-ENGINEERED CAR-T CELLS FOR AUTOIMMUNITY: MULTIPLEXED mRNA TECHNOLOGY FOR IMPROVED MODE-OF-ACTION AND SAFETY
Annals of the Rheumatic Diseases·2025Open Access
Author Correction: Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells
Genome biology·2025Open Access
TGFβ links EBV to multisystem inflammatory syndrome in children
Nature·2025· 23 citedOpen Access
Gene editing of CD3 epsilon to redirect regulatory T cells for adoptive T cell transfer
Molecular Therapy·2025· 8 citedOpen Access
Revisiting the Need for mRNA Nucleoside Modification in CAR T Cell Engineering
2025· 1 citedOpen Access
Lung tumoroids as a testing platform for precision CAR T-cell therapy
2025Open Access
Additional file 2 of Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells
Figshare·2025Open Access
Engineering a solution for allogeneic CAR-T rejection
Molecular Therapy·2024· 1 citedOpen Access
Effector memory–type regulatory T cells display phenotypic and functional instability
Science Advances·2024· 12 citedOpen Access
The rise of patient avatars in precision oncology
Nature Biotechnology·2024· 5 cited
CAR-T overdrive: harnessing inosine for metabolic rewiring and stemness induction
Signal Transduction and Targeted Therapy·2024· 2 citedOpen Access
Gene editing of <i>CD3 epsilon</i> gene to redirect regulatory T cells for adoptive T cell transfer
2024· 2 citedOpen Access
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Frequent Co-authors

Petra Reinke(38), Hans‐Dieter Volk(34), Dimitrios L. Wagner(20), Leila Amini(20), Nina Babel(13), Weijie Du(13), Jonas Kath(12), Maik Stein(12), Désirée J. Wendering(9), Viktor Glaser(9), Clemens Franke(8), Sybille Landwehr-Kenzel(7), Stephan Schlickeiser(7), Axel Prüß(7), Annette Künkele(7), Vanessa Drosdek(7), Andy Roemhild(6), Julia K. Polansky(6), Levent Akyüz(5), Mohamed Abou‐El‐Enein(5)