Nuno A. Fonseca

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.4kcitations50works18.02yr avg
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Research Topics

RNA Interference and Gene Delivery(16), Advanced biosensing and bioanalysis techniques(14), Nanoparticle-Based Drug Delivery(11), RNA modifications and cancer(10), Cancer Cells and Metastasis(6)

Publications50 total

Bridging membrane fluidity studies with a predictive model of drug encapsulation to address industrial challenges of liposomal injectables manufacturing
Drug Delivery and Translational Research·2025· 4 cited
Rational formulation and industrial manufacturing of lipid-based complex injectables: Landmarks and trends
Journal of Controlled Release·2024· 32 cited
Nucleolin expression has prognostic value in neuroblastoma patients
EBioMedicine·2022· 10 citedOpen Access
Abstract 1276: Nucleolin has prognostic value in neuroblastoma patients
Cancer Research·2022
Nucleolin Overexpression Predicts Patient Prognosis While Providing a Framework for Targeted Therapeutic Intervention in Lung Cancer
Cancers·2022· 8 citedOpen Access
Targeted liposomal doxorubicin/ceramides combinations: The importance to assess the nature of drug interaction beyond bulk tumor cells
European Journal of Pharmaceutics and Biopharmaceutics·2022· 4 cited
The Enhanced Efficacy of Intracellular Delivery of Doxorubicin/C6-Ceramide Combination Mediated by the F3 Peptide/Nucleolin System Is Supported by the Downregulation of the PI3K/Akt Pathway
Cancers·2021· 14 citedOpen Access
Cell surface Nucleolin represents a novel cellular target for neuroblastoma therapy
Journal of Experimental & Clinical Cancer Research·2021· 49 citedOpen Access
Modelling the impact of nucleolin expression level on the activity of F3 peptide-targeted pH-sensitive pegylated liposomes containing doxorubicin
Drug Delivery and Translational Research·2021· 11 cited
GMP-grade nanoparticle targeted to nucleolin downregulates tumor molecular signature, blocking growth and invasion, at low systemic exposure
Nano Today·2021· 25 citedOpen Access
Cancer Stem Cells and Nucleolin as Drivers of Carcinogenesis
Pharmaceuticals·2021· 47 citedOpen Access
In Vitro and In Vivo Tumor Models for the Evaluation of Anticancer Nanoparticles
Advances in experimental medicine and biology·2021· 12 cited
Abstract LB-274: Primary tumor gene expression signature predicts long-term outcomes in primary melanoma: A prospective multicenter study
Cancer Research·2020
Current challenges and emerging opportunities of CAR-T cell therapies
Journal of Controlled Release·2019· 149 cited
Abstract A101: Nucleolin: A novel cell surface protein for neuroblastoma targeted therapy
Molecular Cancer Therapeutics·2019
Abstract 2994: In vivo targeting of mesothelioma’s molecular signature with nanoparticle functionalized with nucleolin-binding peptide
Cancer Research·2019
Nucleolin-based targeting strategies for cancer therapy: from targeted drug delivery to cytotoxic ligands
Drug Discovery Today·2019· 92 cited
Abstract 3622: Differential effect of liposomal C6-ceramide/doxorubicin targeted to nucleolin and conventional combinations against triple negative breast cancer stem cells
Cancer Research·2019· 1 cited
Using Deep Learning for prediction of protein abundance from RNA concentrations and Gene Ontology annotations
Research in Computational Molecular Biology·2018
Expression Atlas: exploring gene expression at tissue and single cell level across species and biological conditions
Faculty of 1000 Research Ltd·2018Open Access
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Frequent Co-authors

João Nuno Moreira(39), Sérgio Simões(25), Vera Moura(23), Ana F. Cruz(12), Ana C. Gregório(9), Nélson Monteiro(7), Albino Martins(7), Nuno M. Neves(7), Nélio Gonçalves(7), Ângela Valério-Fernandes(7), Rui L. Reis(6), Susana Faria(5), Veronica Bensa(4), Patrizia Perri(4), Mirco Ponzoni(4), Fabio Pastorino(4), Rui M. Lopes(4), Lígia C. Gomes‐da‐Silva(3), Teresa R. Abreu(3), Diana Ribeiro(3)