Alexandre Prat

National Institutes of Health — United States

Medicine · Health Sciences

83h-index29.4kcitations434works5.82yr avg
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Research Topics

Multiple Sclerosis Research Studies(177), Neuroinflammation and Neurodegeneration Mechanisms(104), Barrier Structure and Function Studies(46), Immunotherapy and Immune Responses(39), Immune Response and Inflammation(38)

Publications433 total

Managing reactivation of multiple sclerosis during treatment with natalizumab
Multiple Sclerosis Journal·2025Open Access
Oxidized phosphatidylcholines deposition drives chronic neurodegeneration in a mouse model of progressive multiple sclerosis via IL-1β signaling
Nature Neuroscience·2025
Cerebrospinal fluid-driven ependymal motile cilia defects are implicated in multiple sclerosis
Brain·2025Open Access
Bruton’s tyrosine kinase inhibitors rescue neuronal impairment caused by B cell–mediated lymphotoxin-α release
Science Translational Medicine·2025
Moderate–high efficacy disease-modifying therapies reduce relapse risk in late-onset multiple sclerosis
Journal of Neurology Neurosurgery & Psychiatry·2025
YI6 MS outcomes in breast cancer survivors and the influence of chemotherapy
2025Open Access
Disease course after pregnancy in women with progressive multiple sclerosis symptoms
Multiple Sclerosis Journal·2025Open Access
Machine learning using clinical variables to screen for depression and anxiety in people with early multiple sclerosis
Multiple Sclerosis and Related Disorders·2025· 1 citedOpen Access
Pregnancy-Related Disease Outcomes in Women With Moderate to Severe Multiple Sclerosis Disability
JAMA Network Open·2025Open Access
Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology
Nature·2025Open Access
Clinical and mechanistic effects of cladribine in relapsing multiple sclerosis: 2-year results from the MAGNIFY-MS Study
Therapeutic Advances in Neurological Disorders·2025· 5 citedOpen Access
Personalized federated learning for predicting disability progression in multiple sclerosis using real-world routine clinical data
npj Digital Medicine·2025· 4 citedOpen Access
Mannose Receptor C type 2 influences autoimmune neuroinflammation and blood-brain barrier integrity
2025Open Access
Four years on: Pregnancy and birth outcomes reported in the MSBase pregnancy, neonatal outcomes, and Women’s Health Registry (2020–2024)
Multiple Sclerosis Journal·2025Open Access
Cerebrospinal fluid-driven ependymal motile cilia defects are implicated in multiple sclerosis pathophysiology
2025· 1 citedOpen Access
Summary of Research: Blood Biomarker Dynamics in People with Relapsing Multiple Sclerosis Treated with Cladribine Tablets: Results of the 2-Year MAGNIFY-MS Study
Neurology and Therapy·2025Open Access
Peripheral HLA-DR <sup>hi</sup> CD141 <sup>+</sup> Classical Monocytes Predict Relapse Risk and Worsening in Multiple Sclerosis
Neurology Neuroimmunology & Neuroinflammation·2025Open Access
Cervical Spinal Cord Magnetization Transfer Ratio and Its Relationship With Clinical Outcomes in Multiple Sclerosis
Annals of Clinical and Translational Neurology·2025Open Access
First-Line Use of Higher-Efficacy Disease-Modifying Therapies in Multiple Sclerosis: Canadian Consensus Recommendations
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques·2025· 1 citedOpen Access
Detection of astrocyte epigenetic memory in <i>in vitro</i> systems, experimental autoimmune encephalomyelitis and multiple sclerosis samples
2025· 1 citedOpen Access
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Frequent Co-authors

Jack P. Antel(15), Jorge I. Alvarez(13), Hania Kébir(12), Francisco J. Quintana(8), Pierre Duquette(8), Romain Cayrol(7), Guillermo Izquierdo(7), Stéphanie Zandee(7), Amit Bar‐Or(7), Igal Ifergan(6), Monique Bernard(6), Nathalie Arbour(6), Veit Rothhammer(6), Karolina Wosik(6), Eva Havrdová(6), Marc Girard(6), María Trojano(6), Alessandra Lugaresi(6), Roberto Bergamaschi(6), Pierre Grammond(6)