Edward L. Bolt

University of Nottingham — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index1.6kcitations98works1.12yr avg
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Research Topics

DNA Repair Mechanisms(41), CRISPR and Genetic Engineering(35), Bacterial Genetics and Biotechnology(28), Photosynthetic Processes and Mechanisms(13), DNA and Nucleic Acid Chemistry(13)

Publications98 total

Saccharin disrupts bacterial cell envelope stability and interferes with DNA replication dynamics
EMBO Molecular Medicine·2025· 3 citedOpen Access
The human HELQ helicase and XRN2 exoribonuclease cooperate in R-loop resolution
Open Biology·2025· 1 citedOpen Access
Author response for "The human HELQ helicase and XRN2 exoribonuclease cooperate in R-loop resolution"
2025
Identification of a novel nuclease activity in human DDX49 helicase
Royal Society Open Science·2024Open Access
POLD3 as Controller of Replicative DNA Repair
International Journal of Molecular Sciences·2024· 4 citedOpen Access
Author response for "Identification of a novel nuclease activity in human DDX49 helicase"
2024
Author response for "Identification of a novel nuclease activity in human DDX49 helicase"
2024
Repurposing Proximity-Dependent Protein Labeling (BioID2) for Protein Interaction Mapping in E. coli
Methods in molecular biology·2024· 1 citedOpen Access
<i>Escherichia coli</i><scp>DNA</scp> repair helicase Lhr is also a <scp>uracil‐DNA</scp> glycosylase
Molecular Microbiology·2023· 1 citedOpen Access
Archaeal Hel308 suppresses recombination through a catalytic switch that controls DNA annealing
Nucleic Acids Research·2023· 6 citedOpen Access
Cas1–Cas2 physically and functionally interacts with DnaK to modulate CRISPR Adaptation
Nucleic Acids Research·2023· 5 citedOpen Access
Editorial: Structural biology of nucleic acid replication, recombination and repair
Frontiers in Molecular Biosciences·2023Open Access
CRISPR-Cas adaptation in <i>Escherichia coli</i>
Bioscience Reports·2023· 8 citedOpen Access
E. coli DNA Repair Helicase Lhr is also a Uracil-DNA Glycosylase
2023Open Access
Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing
Nucleic Acids Research·2023· 8 citedOpen Access
Human HelQ and DNA polymerase δ interact to halt DNA synthesis and stimulate DNA single-strand annealing
2022Open Access
Faculty Opinions recommendation of How Escherichia coli Became the Flagship Bacterium of Molecular Biology.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2022
Faculty Opinions recommendation of Recombination by replication.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2022
Faculty Opinions recommendation of Cas1 and fen1 display equivalent functions during archaeal DNA repair.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2022
Faculty Opinions recommendation of Type I CRISPR-Cas provides robust immunity but incomplete attenuation of phage-induced cellular stress.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2022
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Frequent Co-authors

Ivana Ivančić-Baće(12), Robert G. Lloyd(10), Tom Killelea(6), Gary J. Sharples(6), Martin J. Warren(4), Simon Cass(4), Jamieson A. L. Howard(4), He Liu(4), Marin Radovčić(4), Isabel Woodman(4), Panos Soultanas(4), Andrew Cubbon(3), Tabitha Jenkins(3), Sarah Northall(3), Rebecca Lever(3), Ryan J. Buckley(3), Sarah C. Woodcock(2), Matthew C. Whitby(2), Sau N. Chan(2), Geoffrey S. Briggs(2)