Max L. Birnstiel

University of North Carolina at Chapel Hill — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

74h-index19.9kcitations205works0.02yr avg
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Research Topics

RNA and protein synthesis mechanisms(80), RNA Research and Splicing(49), RNA modifications and cancer(45), DNA and Nucleic Acid Chemistry(39), RNA Interference and Gene Delivery(34)

Publications205 total

Gene Transfer to Respiratory Epithelial Cells via the Receptor-mediated Endocytosis Pathway
UNC Libraries·2021Open Access
Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.
UNC Libraries·2020· 10 citedOpen Access
High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.
UNC Libraries·2020· 10 citedOpen Access
(histone genes/RNA processing/palindrome/small nuclear ribonucleo
2016
Erratum to “The dawn of gene isolation” [Gene 300 (2003) 3–11]
Gene·2004
The artificial antimicrobial peptide KLKLLLLLKLK induces predominantly a TH2-type immune response to co-injected antigens
Vaccine·2004· 97 cited
The modulator is a constitutive enhancer of a developmentally regulated sea urchin histone H2A gene (vol 24, pg 850, 2002)
Annali Italiani di Chirurgia·2003
The dawn of gene isolation
Gene·2002· 3 cited
The modulator is a constitutive enhancer of a developmentally regulated sea urchin histone H2A gene
BioEssays·2002· 6 cited
Vaccination with poly-L-arginine as immunostimulant for peptide vaccines: induction of potent and long-lasting T-cell responses against cancer antigens.
PubMed·2002· 50 cited
In vitro evaluation of a tumor vaccine based on the xenogenization of tumor cells with tetanus toxoid molecules
European Journal of Cancer·1999
Immunotherapy of Metastatic Malignant Melanoma by a Vaccine Consisting of Autologous Interleukin 2-Transfected Cancer Cells: Outcome of a Phase I Study
Human Gene Therapy·1999· 127 cited
Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene
Journal of Molecular Medicine·1997· 14 cited
Transloading of tumor antigen-derived peptides into antigen-presenting cells
Proceedings of the National Academy of Sciences·1997· 53 cited
Cell-free tumor antigen peptide-based cancer vaccines
Proceedings of the National Academy of Sciences·1997· 52 cited
The Five Cleavage-Stage (CS) Histones of the Sea Urchin Are Encoded by a Maternally Expressed Family of Replacement Histone Genes: Functional Equivalence of the CS H1 and Frog H1M (B4) Proteins
Molecular and Cellular Biology·1997· 50 citedOpen Access
Generation of effective cancer vaccines genetically engineered to secrete cytokines using adenovirus-enhanced transferrinfection (AVET)
Gene·1997· 13 cited
Preparation of Adenovirus‐Polylysine‐DNA Complexes
Current Protocols in Human Genetics·1996· 9 cited
The genetic revolution 1950–1996: an introduction
European Review·1996
Gene therapy
European Review·1996· 1 cited
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Frequent Co-authors

Ernst Wagner(12), Matthew Cotten(12), Kurt Zatloukal(4), Helen Kirlappos(4), Karl Mechtler(4), Rudolf Grosschedl(4), Meinrad Busslinger(3), Martin Zenke(3), Hartmut Beug(3), I. F. Purdom(3), Carmen Birchmeier(3), Katharina Strub(2), Hamilton O. Smith(2), K. W. Jones(2), Christopher C. Hentschel(2), Gabriella Galli(2), Hans Hofstetter(2), David T. Curiel(2), Jim Speirs(2), Ulrich E. Loening(2)