Dennis L. Sprecher

Cure HHT — United States

Medicine · Health Sciences

51h-index11.6kcitations185works3.02yr avg
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Research Topics

Lipoproteins and Cardiovascular Health(65), Diabetes, Cardiovascular Risks, and Lipoproteins(40), Obesity, Physical Activity, Diet(16), Adipose Tissue and Metabolism(11), Diet and metabolism studies(11)

Publications185 total

1.7-micron Optical Coherence Tomography Angiography for Diagnosis and Monitoring of Hereditary Hemorrhagic Telangiectasia - A Pilot Study
IEEE Transactions on Biomedical Engineering·2024· 3 citedOpen Access
Evaluation of GSK2789917-induced TRPV4 inhibition in animal models of fluid induced lung injury
Naunyn-Schmiedeberg s Archives of Pharmacology·2023· 4 cited
1.7-micron optical coherence tomography angiography (OCTA) for characterization of hereditary hemorrhagic telangiectasia (HHT) lesions
2023
Evaluation of Dynamic <scp>Contrast‐Enhanced MRI</scp> Measures of Lung Congestion and Endothelial Permeability in Heart Failure: A Prospective Method Validation Study
Journal of Magnetic Resonance Imaging·2022· 2 citedOpen Access
TRPV4 Specific Inhibition Ameliorates Fluid-Induced Lung Injury
SSRN Electronic Journal·2022Open Access
Pazopanib for severe bleeding and transfusion-dependent anemia in hereditary hemorrhagic telangiectasia
Angiogenesis·2021· 44 citedOpen Access
Identification of a Human Whole Blood–Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo
Journal of Pharmacology and Experimental Therapeutics·2020· 2 citedOpen Access
Correction to: Development of a conceptual model and patient-reported outcome measures for assessing symptoms and functioning in patients with heart failure
Quality of Life Research·2020· 1 citedOpen Access
Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia
Annals of Internal Medicine·2020· 467 cited
Development of a conceptual model and patient-reported outcome measures for assessing symptoms and functioning in patients with heart failure
Quality of Life Research·2020· 7 citedOpen Access
Assessing the Impact of Losmapimod on Proteinuria in Idiopathic Focal Segmental Glomerulosclerosis
Kidney International Reports·2020· 8 citedOpen Access
Targeting Pulmonary Capillary Permeability to Reduce Lung Congestion in Heart Failure: A Randomized, Controlled Pilot Trial
European Journal of Heart Failure·2020· 46 citedOpen Access
Heart Failure Patient-Reported Outcome Measures
PsycTESTS Dataset·2020
Issue Information
Clinical Pharmacology in Drug Development·2019· 1 citedOpen Access
A Randomized, Placebo‐Controlled Trial to Assess the Effects of 8 Weeks of Administration of GSK256073, a Selective GPR109A Agonist, on High‐Density Lipoprotein Cholesterol in Subjects With Dyslipidemia
Clinical Pharmacology in Drug Development·2019· 11 cited
The Burden of Congestion in Patients Hospitalized With Acute Decompensated Heart Failure
The American Journal of Cardiology·2019· 41 cited
Clinical Pharmacokinetics, Safety, and Tolerability of a Novel, First-in-Class TRPV4 Ion Channel Inhibitor, GSK2798745, in Healthy and Heart Failure Subjects
American Journal of Cardiovascular Drugs·2019· 139 citedOpen Access
Nosebleeds in hereditary hemorrhagic telangiectasia: Development of a patient‐completed daily eDiary
Laryngoscope Investigative Otolaryngology·2018· 8 citedOpen Access
Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia
Angiogenesis·2018· 99 citedOpen Access
Development of Focal Segmental Glomerulosclerosis Patient-Reported Outcome Measures: Symptom Diary and Symptom Impact Questionnaire
American Journal of Kidney Diseases·2017· 15 cited
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Frequent Co-authors

Gregory L. Pearce(7), John A. Morrison(7), Richard E. Gregg(5), Stephen R. Daniels(4), Loren A. Zech(4), Jeffrey M. Hoeg(4), Bruce Barton(4), Lea Sarov‐Blat(4), John J. Lepore(4), Marc S. Penn(3), Stanley L. Hazen(3), Philip R. Khoury(3), H Bryan Brewer(3), Frank M. Biro(3), Robert N. Willette(3), Joseph Cheriyan(3), Michael P. Dubé(2), Judith A. Aberg(2), W. Keith Henry(2), Judith S. Currier(2)