Wendy A. Offen

University of York — United Kingdom

Chemistry · Physical Sciences

20h-index1.9kcitations64works2.72yr avg
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Research Topics

Carbohydrate Chemistry and Synthesis(22), Enzyme Production and Characterization(19), Glycosylation and Glycoproteins Research(14), Biofuel production and bioconversion(12), Microbial Metabolites in Food Biotechnology(11)

Publications64 total

Signal-strapping as a protein-sequence search method for the discovery of metalloproteins
Nature Communications·2025Open Access
Bespoke Activity-Based Probes Reveal that the <i>Pseudomonas aeruginosa</i> Endoglycosidase, PslG, Is an Endo-β-glucanase
Journal of the American Chemical Society·2025· 4 citedOpen Access
Selective labelling of GBA2 in cells with fluorescent β-<scp>d</scp>-arabinofuranosyl cyclitol aziridines
Chemical Science·2024· 4 citedOpen Access
β-<scp>l</scp>-<i>Arabino</i>furano-cyclitol Aziridines Are Covalent Broad-Spectrum Inhibitors and Activity-Based Probes for Retaining β-<scp>l</scp>-Arabinofuranosidases
ACS Chemical Biology·2023· 8 citedOpen Access
A Multiplexing Activity-Based Protein-Profiling Platform for Dissection of a Native Bacterial Xyloglucan-Degrading System
ACS Central Science·2023· 9 citedOpen Access
A multiplexing activity-based protein profiling platform for dissection of a native bacterial xyloglucan-degrading system
2023· 1 citedOpen Access
The development of a broad-spectrum retaining β-exo-galactosidase activity-based probe
Organic & Biomolecular Chemistry·2023· 6 citedOpen Access
Synthesis of broad-specificity activity-based probes for <i>exo</i>-β-mannosidases
Organic & Biomolecular Chemistry·2021· 13 citedOpen Access
CCDC 2018297: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents
Chemistry - A European Journal·2021· 11 citedOpen Access
Development of Non‐Hydrolysable Oligosaccharide Activity‐Based Inactivators for Endoglycanases: A Case Study on α‐1,6 Mannanases
Chemistry - A European Journal·2021· 5 citedOpen Access
Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C-5a-Substituted Derivatives of 4-epi-Isofagomine
Molecules·2020· 13 citedOpen Access
Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-fluorinated Monosaccharides
Cell chemical biology·2020· 22 citedOpen Access
Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-Fluorinated Monosaccharides
2020· 1 citedOpen Access
Profiling Substrate Promiscuity of Wild-Type Sugar Kinases for Multi-Fluorinated Monosaccharides
2020· 1 citedOpen Access
Discovery of a Fungal Copper Radical Oxidase with High Catalytic Efficiency toward 5-Hydroxymethylfurfural and Benzyl Alcohols for Bioprocessing
ACS Catalysis·2020· 68 citedOpen Access
Crystal structure of a galactokinase from Bifidobacterium infantis in complex with 2-deoxy-2-fluoro-galactose
2019
Crystal structure of a galactokinase from Bifidobacterium infantis in complex with ADP
2019
Copper oxidase from Colletotrichum graminicola
2019
Structure of Papaver somniferum O-methyltransferase 1 reveals initiation of noscapine biosynthesis
2019
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Frequent Co-authors

G.J. Davies(47), Herman S. Overkleeft(15), Jeroen D. C. Codée(10), Johannes M. F. G. Aerts(9), Marta Artola(8), Thomas J. M. Beenakker(7), Simon J. Charnock(6), Gijsbert A. van der Marel(6), Lianne I. Willems(5), Harry Brumer(5), Liang Wu(5), Tessa Keenan(5), Fabio Parmeggiani(5), Julien Malassis(5), Clément Q. Fontenelle(5), Jean-Baptiste Vendeville(5), Peter Both(5), Alex Heyam(5), Bruno Linclau(5), Sabine L. Flitsch(5)