Paul Kung

National United University — Taiwan

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index515citations43works1.02yr avg
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Research Topics

Peroxisome Proliferator-Activated Receptors(3), Adipose Tissue and Metabolism(3), Block Copolymer Self-Assembly(3), Carbon Nanotubes in Composites(2), Phase Equilibria and Thermodynamics(2)

Publications43 total

Influence of magnetic particle fluid flow field control on droplet evaporation
Applied Thermal Engineering·2025· 1 cited
Inhibitors of Myocyte Triacylglyceride Accumulation
2015
Scheme 1, Synthesis of ML377
2015
Figure 3, Potency of ML377 inhibition for triacylglycerol accumulation in both H9c2 cells and differentiated human skeletal myotubes
2015
Table 4, Summary of in vitro ADME Properties of TAG inhibitor probe ML377
2015
Table 3, Probe and Analog Submissions to MLSMR (Evotec) for TAG inhibitors
2015
Figure 2, Stability of ML377 in 1× PBS at RT
2015
Figure 1, Structure of ML377
2015
Figure 1, EBI2 antagonist GSK682753
2015
Figure 7, ML400 Prevents Adipogenesis in 3T3-L1 Cells
2015
Small Molecules Targeting the Mitochondrial Permeability Transition
2015· 11 cited
Table 4, Summary of in vitro ADME Properties of selected LMPTP inhibitors
2015
Table 3, Probe and Analog Submissions to MLSMR (Evotec) for Small Molecule Inhibitors of LMPTP
2015
Table 5, Summary of in vitro ADME Properties of EBI2 inhibitor probe ML401 (MLS-0472527)
2015
Scheme 1, Synthesis of ML400, conditions: a. 4-Methoxybenzoyl chloride, DIPEA, DCM, 0°C to RT, overnight (80%); b. t-BuOK, t-BuOH, 75°C, overnight (84%); c. POCl3, 90°C, overnight (61%); d. 3-(Piperidin-1-yl)propan-1-amine, t-BuOK 10%, Dry DMA, 135°C, overnight, nitrogen atmosphere (57%)
2015
Figure 6, Eurofins Panel for ML401
2015
Figure 5, Potency of ML401 inhibition in EBI2 beta-arrestin and RS11846 cell chemotaxis assays
2015
Figure 3, Stability of ML401 in 1×
2015
Functional Antagonists of EBI-2
Europe PMC (PubMed Central)·2015· 2 cited
Table 1, Potency and selectivity characteristics for probe ML400
2015
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Frequent Co-authors

Anthony B. Pinkerton(26), Arianna Mangravita-Novo(26), Layton H. Smith(26), Thomas D.Y. Chung(26), Stefan Vasile(24), Eigo Suyama(24), Sumeet Salaniwal(21), Kevin Nguyen(18), Robert Ardecky(16), Santhi Ganji(16), Eduard Sergienko(15), Jiwen Zou(13), Michael P. Hedrick(9), Palak Gosalia(9), Monika Milewski(9), Satyamaheshwar Peddibhotla(8), Paul Hershberger(8), Fusayo Yamamoto(8), Nikki Barron(8), Elliot Sugarman(8)