Marina Scheller

Heidelberg University — Germany

Medicine · Health Sciences

18h-index2.5kcitations44works10.02yr avg
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Research Topics

Acute Myeloid Leukemia Research(17), Epigenetics and DNA Methylation(7), Cancer-related gene regulation(7), Hematopoietic Stem Cell Transplantation(6), Immune Cell Function and Interaction(6)

Publications44 total

Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging mice
Cell Reports·2025· 13 citedOpen Access
Depletion of CD8+ CAR T-cells leads to superior anti-tumor efficacy of pure CD4+ CAR T-cells against Acute Leukemias
2025Open Access
P-03.04 Targeting CXCR4: implications for clonal dynamics and MRD assessment in acute myeloid leukemia
Poster presentations·2025Open Access
Mapping Genotype to Phenotype in Clonal Hematopoiesis Uncovers Downregulated MHC-II Molecules in <i>DNMT3AR882</i> - Mutant Hematopoietic Stem Cells
Blood·2024· 1 cited
Clonal Dynamics of Leukemic and Clonal Hematopoiesis Mutations Predict Relapse in Single Cell MRD Analysis of AML in First Complete Remission
Blood·2024Open Access
Metabolic alterations drive inflammatory phenotypes in CHIP-associated heart failure
2024Open Access
DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts
Nature Communications·2024· 56 citedOpen Access
Monocyte-derived microglia with <i>Dnmt3a</i> mutation cause motor pathology in aging mice
2023· 8 citedOpen Access
Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis
Nature Communications·2023· 52 citedOpen Access
DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts
2023· 12 citedOpen Access
Ethanol-Mediated Bone Marrow Toxicity and Impaired Erythropoiesis: Implications for Alcohol-Related Liver Disease
2023· 4 cited
Double-Blind, Placebo Controlled, Randomized, Multicenter, Phase II Study to Assess the Efficacy of the High Affinity CXCR4 Inhibitor BL-8040 As Addition to Consolidation Therapy in AML By the SAL and OSHO Leukemia Study Groups
Blood·2022· 4 cited
Impact of the transcription factor IRF8 on limbal epithelial progenitor cells in a mouse model
Experimental Eye Research·2022· 8 citedOpen Access
Inflammatory signals from fatty bone marrow supports the early stages of <i>DNMT3a</i> driven clonal hematopoiesis
2022· 1 citedOpen Access
Fatty Bone Marrow Positively Selects Pre-Leukemic HSPCs with a <i>DNMT3A-</i>mutation
Blood·2021· 4 cited
Hotspot DNMT3A mutations in Clonal Hematopoiesis and Acute Myeloid Leukemia sensitize cells to Azacytidine via viral mimicry response
2021· 3 citedOpen Access
Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response
Nature Cancer·2021· 70 cited
PS969 HYPOMETHYLATING DRUGS SPECIFICALLY TARGET DNMT3A MUTATION ASSOCIATED CLONAL HEMATOPOIESIS AND ACUTE MYELOID LEUKEMIA
HemaSphere·2019Open Access
IRE1α maintains HSC stemness under ER-stress
Nature Cell Biology·2019· 5 cited
BET-inhibition by JQ1 promotes proliferation and self-renewal capacity of hematopoietic stem cells
Haematologica·2018· 32 citedOpen Access
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Frequent Co-authors

Carsten Müller‐Tidow(18), Achim Leutz(10), Frank Rosenbauer(8), Christian Rohde(6), Ivan D. Horak(5), Hubert Serve(5), Inga Hemmerling(5), Florian Leuschner(5), Daniel B. Lipka(5), Nathali Kaushansky(5), Nicole Bäumer(4), Liran I. Shlush(4), Marco Prinz(3), Joerg Huelsken(3), Walter Birchmeier(3), Christoph Plass(3), Jürgen Löhler(3), Carol Stocking(3), Anne K. Ludwig(3), Christian Arnold(3)