Keqiang Ye

Emory University — United States

Medicine · Health Sciences

80h-index22.8kcitations351works10.32yr avg
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Research Topics

Alzheimer's disease research and treatments(78), Nerve injury and regeneration(40), PI3K/AKT/mTOR signaling in cancer(35), Peptidase Inhibition and Analysis(33), Parkinson's Disease Mechanisms and Treatments(30)

Publications349 total

Galectin-9 activates the TLR4-NLRP3 inflammasome pathway and promotes tau pathology in Alzheimer’s disease
Brain Behavior and Immunity·2025· 1 citedOpen Access
eLife Assessment: Chronic stress impairs autoinhibition in neurons of the locus coeruleus to increase asparagine endopeptidase activity
2025Open Access
Gut-induced alpha-Synuclein and Tau propagation initiate Parkinson’s and Alzheimer’s disease co-pathology and behavior impairments
Neuron·2025Open Access
eLife Assessment: Chronic stress impairs autoinhibition in neurons of the locus coeruleus to increase asparagine endopeptidase activity
2025Open Access
Development of Positron Emission Tomography Radiotracers for Imaging α-Synuclein Aggregates
Cells·2025· 5 citedOpen Access
Correction to: Cellular energy stress induces AMPK-mediated regulation of glioblastoma cell proliferation by PIKE-A phosphorylation
Cell Death and Disease·2025Open Access
Targeting FSH for osteoporosis, obesity, and Alzheimer’s disease
Trends in Molecular Medicine·2025Open Access
Immunotherapy against tau fragment diminishes AD pathology, improving synaptic function and cognition
Molecular Neurodegeneration·2025· 1 citedOpen Access
Asparagine endopeptidase cleaves apolipoprotein A1 and accelerates pathogenesis of atherosclerosis
Journal of Clinical Investigation·2025· 2 citedOpen Access
eLife Assessment: Chronic stress impairs autoinhibition in neurons of the locus coeruleus to increase asparagine endopeptidase activity
2025Open Access
Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT
Advanced Science·2025Open Access
eLife Assessment: APP β-CTF triggers cell-autonomous synaptic toxicity independent of Aβ
2025Open Access
eLife assessment: Simply crushed zizyphi spinosi semen prevents neurodegenerative diseases and reverses age-related cognitive decline in mice
2025Open Access
Distinct factors drive the progression of tau pathology in Alzheimer’s disease
Fundamental Research·2025· 2 citedOpen Access
Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances
Signal Transduction and Targeted Therapy·2025· 84 citedOpen Access
eLife Assessment: APP β-CTF triggers cell-autonomous synaptic toxicity independent of Aβ
2025Open Access
Asparagine Endopeptidase Inhibition Attenuates Tissue Plasminogen Activator‐Induced Brain Hemorrhagic Transformation After Ischemic Stroke
CNS Neuroscience & Therapeutics·2025· 5 citedOpen Access
Neuronal FAM171A2 mediates α-synuclein fibril uptake and drives Parkinson’s disease
Science·2025· 44 cited
Microglia Process α‐Synuclein Fibrils and Enhance their Pathogenicity in a TREM2‐Dependent Manner (Adv. Sci. 7/2025)
Advanced Science·2025Open Access
Propagation of pathologic α-synuclein from kidney to brain may contribute to Parkinson’s disease
Nature Neuroscience·2025· 44 cited
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Frequent Co-authors

Xia Liu(19), Zhentao Zhang(9), Seong Su Kang(9), Sung‐Wuk Jang(7), Hongbo R. Luo(7), Solomon H. Snyder(5), Ge� Xiao(4), Mingke Song(4), Yi Sun(4), Fadlo R. Khuri(4), Shan Ping Yu(4), Zhi-Hao Wang(4), Fredric P. Manfredsson(4), Duc M. Duong(3), Nicholas T. Seyfried(3), Jian‐Zhi Wang(3), Shan Ping Yu(3), Taro Hitosugi(3), Lu Zhou(3), Shannon Elf(3)