Samir M. Hamdan

Biochemistry, Genetics and Molecular Biology · Life Sciences

33h-index5.3kcitations151works3.92yr avg
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Research Topics

DNA Repair Mechanisms(67), DNA and Nucleic Acid Chemistry(57), Bacterial Genetics and Biotechnology(30), Advanced biosensing and bioanalysis techniques(24), Bacteriophages and microbial interactions(13)

Publications151 total

Real-time imaging of rotation during synthesis by the replisome
Science Advances·2026Open Access
PAF15 stabilizes PCNA on DNA and slows down its sliding dynamics
2025Open Access
Structure of the human CTF18−RFC clamp loader bound to PCNA
2025Open Access
Author response: Structure of the human CTF18−RFC clamp loader bound to PCNA
2025Open Access
smDeepFLUOR: Single-Molecule Deep Learning Fluorescence Classification
2025Open Access
Real-time imaging of rotation during synthesis by the replisome
2025· 1 citedOpen Access
Structural dynamics of DNA unwinding by a replicative helicase
Nature·2025· 11 citedOpen Access
Structure of the human CTF18−RFC clamp loader bound to PCNA
eLife·2024Open Access
Structure of the human CTF18 clamp loader bound to PCNA
2024· 1 citedOpen Access
Revised mechanism of hydroxyurea-induced cell cycle arrest and an improved alternative
Proceedings of the National Academy of Sciences·2024· 27 citedOpen Access
Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair
Nature Communications·2024· 13 citedOpen Access
Switching the Stereopreference of <i>Te</i>SADH: Enabling Anti‐Prelog Asymmetric Reduction of Aryl‐Ring‐Containing Ketones
European Journal of Organic Chemistry·2024Open Access
Enantiocomplementary Asymmetric Reduction of 2–Haloacetophenones Using <i>Te</i>SADH: Synthesis of Enantiopure 2-Halo-1-arylethanols
ACS Omega·2024Open Access
Single-molecule characterization of SV40 replisome and novel factors: human FPC and Mcm10
Nucleic Acids Research·2024· 2 citedOpen Access
Structure of <i>Aquifex aeolicus</i> lumazine synthase by cryo-electron microscopy to 1.42 Å resolution
IUCrJ·2024· 1 citedOpen Access
Severe Combined Immunodeficiency from a Homozygous DNA Ligase 1 Mutant with Reduced Catalytic Activity but Increased Ligation Fidelity
Journal of Clinical Immunology·2024· 9 citedOpen Access
Structure of the human CTF18–RFC clamp loader bound to PCNA
2024· 1 citedOpen Access
Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks
BMC Biology·2024· 11 citedOpen Access
Structural visualisation of the dynamics of DNA unwinding by a replicative helicase
2024Open Access
Structure of <i>Aquifex aeolicus</i> Lumazine Synthase by Cryo-Electron Microscopy to 1.42Å Resolution
2024Open Access
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Frequent Co-authors

Muhammad Tehseen(14), Charles C. Richardson(12), Masateru Takahashi(12), Nicholas E. Dixon(9), Antoine M. van Oijen(8), Fahad Rashid(8), Mohamed A. Sobhy(8), Vlad‐Stefan Raducanu(6), Manal S. Zaher(6), Slobodan Jergic(5), Zahir Ali(5), Magdy M. Mahfouz(5), Susan E. Tsutakawa(4), John A. Tainer(4), Luay Joudeh(4), Musa Musa(4), Nathan A. Tanner(3), Ahmed Mahas(3), Tin Maršić(3), Claudia Lancey(3)