Kay Castagnoli

Virginia Tech — United States

Medicine · Health Sciences

31h-index3.4kcitations60works0.02yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(23), Anesthesia and Sedative Agents(12), Adenosine and Purinergic Signaling(7), Antibiotics Pharmacokinetics and Efficacy(5), Neurotransmitter Receptor Influence on Behavior(4)

Publications60 total

Neurotoxicity studies with the monoamine oxidase B substrate 1-methyl-3-phenyl-3-pyrroline
Life Sciences·2007· 9 cited
Monoamine oxidase B inhibition and neuroprotection
Neurology·2003· 35 cited
Neuroprotection by caffeine and more specific A<sub>2A</sub>receptor antagonists in animal models of Parkinson’s disease
Neurology·2003· 132 cited
Tobacco Leaf, Smoke and Smoking, MAO Inhibitors, Parkinson's Disease and Neuroprotection; Are There Links?
NeuroToxicology·2003· 55 cited
Inhibition of human MAO-A and MAO-B by a compound isolated from flue-cured tobacco leaves and its neuroprotective properties in the MPTP mouse model of neurodegeneration
Inflammopharmacology·2003· 23 cited
Inhibition of monoamine oxidase B by selective adenosine A2A receptor antagonists
Bioorganic & Medicinal Chemistry·2003· 108 cited
8-(3-Chlorostyryl)caffeine May Attenuate MPTP Neurotoxicity through Dual Actions of Monoamine Oxidase Inhibition and A2A Receptor Antagonism
Journal of Biological Chemistry·2002· 116 citedOpen Access
Synthesis and Biological Evaluation of MAO-A Selective 1,4-Disubstituted-1,2,3,6-tetrahydropyridinyl Substrates
Bioorganic & Medicinal Chemistry·2002· 28 cited
Studies on the interactions of tobacco leaf and tobacco smoke constituents and monoamine oxidase
Neurotoxicity Research·2002· 46 cited
Enhancement of auditory sensory gating and stimulus-bound gamma band (40 Hz) oscillations in heavy tobacco smokers
Neuroscience Letters·2002· 63 cited
STUDIES ON THE OXIDATION OF 1,4-DISUBSTITUTED-1,2,3,6-TETRAHYDROPYRIDINES
Drug Metabolism Reviews·2002· 5 cited
Metabolic studies on haloperidol and its tetrahydropyridinyl dehydration product (HPTP) in C57BL/6 mouse brain preparations
Neurotoxicity Research·2002· 9 cited
Rescue of Dying Neurons by (<i>R</i>)‐Deprenyl in the MPTP‐Mouse Model of Parkinson's Disease Does Not Include Restoration of Neostriatal Dopamine
Annals of the New York Academy of Sciences·2001· 1 cited
Neuroprotection by Caffeine and A<sub>2A</sub>Adenosine Receptor Inactivation in a Model of Parkinson's Disease
Journal of Neuroscience·2001· 442 citedOpen Access
Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.
PubMed·2001· 509 citedOpen Access
Neuroprotection in the MPTP Parkinsonian C57BL/6 Mouse Model by a Compound Isolated from Tobacco
Chemical Research in Toxicology·2001· 58 cited
Selective Inhibition of MAO-B through Chronic Low-Dose (R)-Deprenyl Treatment in C57BL/6 Mice Has No Effect on Basal Neostriatal Dopamine Levels
Experimental Neurology·2001· 4 cited
Tobacco affects P50 sensory gating: Auditory event-related potential differences in heavy tobacco smokers and nonsmokers
NeuroImage·2000· 8 cited
Studies on the in Vivo Biotransformation of the Tobacco Alkaloid β-Nicotyrine
Chemical Research in Toxicology·2000· 13 cited
タバコアルカロイド,β‐ニコチリンのin vivo生体内変化に関する研究
Chemical Research in Toxicology·2000
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Frequent Co-authors

Neal Castagnoli(16), Neal Castagnoli(12), Cornelis J. Van der Schyf(10), Jacobus P. Petzer(8), Neal Castagnoli(7), P. Claver Canfell(7), Jiang‐Fan Chen(6), Michael A. Schwarzschild(6), R. D. Miller(6), Mark R. Fahey(5), Dennis M. Fisher(5), Daniel P. Lynam(5), Ronald D. Miller(5), James Arden(4), Stefanus J. Steyn(4), Kui Xu(3), Roland G. W. Staal(3), Patricia K. Sonsalla(3), Stephen M. Rupp(3), Ronald D. Miller(3)