Lawrence J. Shampine

Neuroscience · Life Sciences

16h-index1.1kcitations28works0.02yr avg
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Research Topics

Stress Responses and Cortisol(16), Neuroscience and Neuropharmacology Research(10), Anesthesia and Neurotoxicity Research(6), Pain Mechanisms and Treatments(5), Hormonal Regulation and Hypertension(5)

Publications28 total

Proof-of-Concept Trial with the Neurosteroid Pregnenolone Targeting Cognitive and Negative Symptoms in Schizophrenia
UNC Libraries·2021Open Access
Simultaneous quantification of GABAergic 3α,5α/3α,5β neuroactive steroids in human and rat serum
UNC Libraries·2020Open Access
Neurosteroids and Self-Reported Pain in Veterans Who Served in the U.S. Military after September 11, 2001
UNC Libraries·2020Open Access
Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans
JAMA Network Open·2020· 26 citedOpen Access
(274) Novel Neurosteroid Intervention for Chronic Low Back Pain in Iraq/Afghanistan-Era Veterans
Journal of Pain·2019
Neurosteroid Levels in the Orbital Frontal Cortex of Subjects With PTSD and Controls: A Preliminary Report
Chronic Stress·2019· 22 citedOpen Access
19. Randomized Controlled Trial of a Neurosteroid Intervention in Schizophrenia
Schizophrenia Bulletin·2017· 1 citedOpen Access
(419) Neurosteroid levels are inversely associated with low back pain in female Iraq/Afghanistan-era veterans
Journal of Pain·2016
An exploratory pilot investigation of neurosteroids and self-reported pain in female Iraq/Afghanistan-era Veterans
The Journal of Rehabilitation Research and Development·2016· 9 citedOpen Access
Neurosteroids and Traumatic Brain Injury
2016· 1 cited
Erratum to: DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA’s antidepressant action
Psychopharmacology·2015· 58 citedOpen Access
Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics
Pain Medicine·2015· 17 citedOpen Access
DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA’s antidepressant action
Psychopharmacology·2015· 21 citedOpen Access
Exploratory Investigation of Biomarker Candidates for Suicide in Schizophrenia and Bipolar Disorder
Crisis·2014· 15 cited
(392) Neurosteroid levels are inversely associated with self-reported pain symptoms in U.S. military veterans
Journal of Pain·2014
Neurosteroids and Self-Reported Pain in Veterans Who Served in the U.S. Military after September 11, 2001
Pain Medicine·2010· 31 citedOpen Access
Proof-of-Concept Trial with the Neurosteroid Pregnenolone Targeting Cognitive and Negative Symptoms in Schizophrenia
Neuropsychopharmacology·2009· 190 citedOpen Access
Simultaneous quantification of GABAergic 3α,5α/3α,5β neuroactive steroids in human and rat serum
Steroids·2009· 64 citedOpen Access
Cerebrospinal Fluid Dehydroepiandrosterone Levels Are Correlated with Brain Dehydroepiandrosterone Levels, Elevated in Alzheimer’s Disease, and Related to Neuropathological Disease Stage
The Journal of Clinical Endocrinology & Metabolism·2008· 75 citedOpen Access
Neuroactive steroids, mood stabilizers, and neuroplasticity: alterations following lithium and changes in Bcl-2 knockout mice
The International Journal of Neuropsychopharmacology·2008· 17 citedOpen Access
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Frequent Co-authors

Jason D. Kilts(16), Jennifer C. Naylor(14), Robert M. Hamer(10), Christine E. Marx(9), Brian P. Marx(8), Jennifer L. Strauss(8), A. Leslie Morrow(8), Mark W. Massing(8), Christine E. Marx(8), Steven T. Szabo(8), Jeffrey A. Lieberman(7), Henry R. Wagner(6), Daniel W. Bradford(5), Victoria Payne(5), William T. Trost(5), Marian I. Butterfield(5), Gillian J. Parke(5), Charlotte Dunn(5), Patrizia Porcu(4), David C. Steffens(4)