Alexandre A. Lussier

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index1.3kcitations79works2.32yr avg
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Research Topics

Epigenetics and DNA Methylation(38), Birth, Development, and Health(36), Prenatal Substance Exposure Effects(21), Health, Environment, Cognitive Aging(21), Gestational Diabetes Research and Management(7)

Publications77 total

Prenatal Alcohol Exposure and Mental Health Outcomes: A Two-Sample Mendelian Randomization Study of DNA Methylation Signatures
2026Open Access
A network analysis of housing quality indicators and depression in women
Scientific Reports·2025Open Access
M64. TIMING OF CHILDHOOD ADVERSITY AND EPIGENETIC PATTERNS ACROSS THE FIRST FIVE YEARS: FINDINGS FROM A SOUTH AFRICAN BIRTH COHORT
European Neuropsychopharmacology·2025
M28. A TWO-STEP APPROACH TO EXPLORE TIME-DEPENDENT GENE-ENVIRONMENT INTERACTIONS IN EPIGENOME-WIDE STUDIES
European Neuropsychopharmacology·2025
Can family cohesion and parent-child relationship quality buffer the effects of parental adverse childhood experiences on adolescent epigenetic age acceleration?
2025
Home and epigenome: exploring the role of DNA methylation in the relationship between poor housing quality and depressive symptoms
BMJ Public Health·2025Open Access
Type and developmental timing of childhood adversity predicts psychopathology symptoms in a South African birth cohort
2025Open Access
Strengthening Rigor and Reproducibility in Epigenome-Wide Association Studies of Social Exposures and Brain-Based Health Outcomes
Current Environmental Health Reports·2025· 1 citedOpen Access
Stress reactivity moderates the association between stressful life events and depressive symptoms in adolescents: Results from a population-based study
Journal of Affective Disorders·2024· 1 citedOpen Access
Maximizing insights from longitudinal epigenetic age data: simulations, applications, and practical guidance
Clinical Epigenetics·2024· 2 citedOpen Access
DNA methylation mediates the link between adversity and depressive symptoms
Nature Mental Health·2024· 10 cited
Technical variability across the 450K, EPICv1, and EPICv2 DNA methylation arrays: lessons learned for clinical and longitudinal studies
Clinical Epigenetics·2024· 16 citedOpen Access
Home and Epigenome: DNA Methylation as a Link Between Poor Housing Quality and Depressive Symptoms
2024· 2 citedOpen Access
W67. CLOCK-DEPENDENT ASSOCIATIONS BETWEEN EARLY EXPERIENCES OF POOR HOUSING QUALITY AND CHILDREN'S EPIGENETIC AGE
European Neuropsychopharmacology·2024
Maximizing Insights from Longitudinal Epigenetic Age Data: Simulations, Applications, and Practical Guidance
2024Open Access
Are housing circumstances associated with faster epigenetic ageing? A commentary on Clair <i>et al</i>
Journal of Epidemiology & Community Health·2024Open Access
DNA methylation as a possible mechanism linking childhood adversity and health: results from a 2-sample mendelian randomization study
American Journal of Epidemiology·2024· 10 citedOpen Access
A Meta-Analysis of Sensitive Periods for the Effects of Childhood Adversity on DNA Methylation
Biological Psychiatry·2024
74. A META-ANALYSIS OF SENSITIVE PERIODS FOR THE EFFECTS OF CHILDHOOD ADVERSITY ON DNA METHYLATION
European Neuropsychopharmacology·2023
76. DNA METHYLATION AS A POSSIBLE CAUSAL MECHANISM LINKING CHILDHOOD ADVERSITY AND HEALTH: RESULTS FROM TWO-SAMPLE MENDELIAN RANDOMIZATION STUDY
European Neuropsychopharmacology·2023· 2 cited
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Frequent Co-authors

Erin C. Dunn(28), Esther Walton(16), Andrew Smith(15), Michael S. Kobor(14), Andrew J. Simpkin(13), Matthew Suderman(12), Janine Cerutti(10), Yiwen Zhu(9), Brooke J. Smith(9), Joanne Weinberg(8), Yiwen Zhu(7), Paul Pavlidis(4), Jiaxuan Liu(4), Kerry J. Ressler(4), Min‐Jung Wang(4), Julia L. MacIsaac(3), Albert E. Chudley(3), James N. Reynolds(3), Karmel W. Choi(3), Caroline L. Relton(3)