Volker Hovestadt

Broad Institute — United States

Medicine · Health Sciences

80h-index45.1kcitations353works7.42yr avg
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Research Topics

Glioma Diagnosis and Treatment(114), Cancer Genomics and Diagnostics(73), Epigenetics and DNA Methylation(54), FOXO transcription factor regulation(46), MicroRNA in disease regulation(38)

Publications301 total

A cellular epigenetic classification system for glioblastoma
Neuro-Oncology·2026
Advancing CNS tumor diagnostics with expanded DNA methylation-based classification
Cancer Cell·2025· 3 citedOpen Access
High-throughput single-cell methylation resolves epigenetic states in hematopoietic differentiation and age-related clonal expansions
Blood·2025
Rapid diagnosis of acute leukemia with integrated epigenetic and genetic profiling
Blood·2025
CBFA2T3::GLIS2 directly represses differentiation and is required for AMKL disease maintenance
Blood·2025Open Access
EPCO-52. MACHINE LEARNING AND MULTI-OMIC ANALYSIS IDENTIFY A MICROENVIRONMENT-DRIVEN MENINGIOMA RISK CONTINUUM UNDERLYING MOLECULAR CLASSIFICATIONS
Neuro-Oncology·2025
EXTH-92. Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor-ligand interactions
Neuro-Oncology·2025Open Access
PTHP-21. Nanopore DNA Methylation Sequencing Simulates Rapid Intraoperative Diagnosis of Pediatric Brain Tumors
Neuro-Oncology·2025Open Access
P10.23.B UNCOVERING THERAPEUTIC VULNERABILITIES IN PEDIATRIC BCOR/L1-DRIVEN CNS TUMORS THROUGH MULTI-OMICS PROFILING
Neuro-Oncology·2025Open Access
In silico purification improves DNA methylation-based classification rates of pediatric low-grade gliomas
Acta Neuropathologica·2025Open Access
CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias
Blood·2025· 3 citedOpen Access
Rapid epigenomic classification of acute leukemia
Nature Genetics·2025· 5 citedOpen Access
Clinical and Molecular Characteristics of 100 Atypical Teratoid Rhabdoid Tumor Patients from Low- and Middle-Income Countries
Cancers·2025Open Access
Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard
Nucleic Acids Research·2025Open Access
Lack of evidence for the transitional cerebellar progenitor
Nature·2025· 2 cited
Advancing CNS tumor diagnostics with expanded DNA methylation-based classification
2025· 3 citedOpen Access
Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor–ligand interactions
Nature Cancer·2025· 3 citedOpen Access
Rapid Epigenomic Classification of Acute Leukemia
Klinische Pädiatrie·2025
Explainable artificial intelligence of DNA methylation-based brain tumor diagnostics
Nature Communications·2025· 20 citedOpen Access
AI-based Personalized Survival Predictions For Ependymoma Patients Using DNA Methylation Profiling
Brain and Spine·2025Open Access
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Frequent Co-authors

Stefan M. Pfister(36), David Jones(34), Andrey Korshunov(31), Marcel Kool(26), Andreas von Deimling(24), Peter Lichter(24), Paul A. Northcott(22), Dominik Sturm(18), Marina Ryzhova(18), David Capper(17), Till Milde(17), Olaf Witt(17), Michael D. Taylor(17), Guido Reifenberger(16), Christel Herold‐Mende(15), Marc Zapatka(14), Roland Eils(14), Daniel Schrimpf(13), Andreas Unterberg(13), Jan Köster(13)