Patrick S. Doyle

Beth Israel Deaconess Medical Center — United States

Engineering · Physical Sciences

78h-index22.7kcitations472works4.02yr avg
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Research Topics

Microfluidic and Capillary Electrophoresis Applications(89), Innovative Microfluidic and Catalytic Techniques Innovation(81), Nanopore and Nanochannel Transport Studies(67), Microfluidic and Bio-sensing Technologies(61), Force Microscopy Techniques and Applications(48)

Publications472 total

Interpretable Deep Learning for Single-Molecule Nanopore Fingerprinting Using Physics-Guided Preprocessing
ACS Sensors·2026
MicroRNA spatial profiling for assessing drug efficacy in <i>BRCA1</i> -related triple-negative breast tumors
2026
Size-Controlled Templating of Stable Drug Nanoparticles from Nanoemulsion Precursors for Versatile Nanoformulation
Chemistry of Materials·2025
High‐Concentration Antibody Formulation via Solvent‐Based Dehydration
Advanced Materials·2025Open Access
Surface-Mediated Self-Assembly of Kinetoplast DNA: Depletion-Driven Dimer Formation and Quasi-2D Dynamics
Langmuir·2025
Data-driven organic solubility prediction at the limit of aleatoric uncertainty
Nature Communications·2025· 10 citedOpen Access
Alginate exopolymer significantly modulates the viscoelastic properties and resilience of bacterial biofilms
npj Biofilms and Microbiomes·2025· 4 citedOpen Access
Organic Solubility Prediction at the Limit of Aleatoric Uncertainty
2025Open Access
Phase behavior of catenated-linear DNA mixtures
Soft Matter·2025· 1 citedOpen Access
High-Throughput Generation of Droplet-Templated Amorphous Solid Dispersions Using Continuous Antisolvent Extraction
SSRN Electronic Journal·2025Open Access
Engineering considerations for next-generation oligonucleotide therapeutics
Nature Chemical Engineering·2024· 12 citedOpen Access
Injectable sustained-release hydrogel for high-concentration antibody delivery
RSC Pharmaceutics·2024· 10 citedOpen Access
Thermogelation of nanoemulsions stabilized by a commercial pea protein isolate: high-pressure homogenization defines gel strength
Soft Matter·2024· 7 citedOpen Access
Bacterial clustering amplifies the reshaping of eutrophic plumes around marine particles: A hybrid data-driven model
PLoS Computational Biology·2024Open Access
Organic Solubility Prediction at the Limit of Aleatoric Uncertainty
2024· 2 citedOpen Access
From burst to controlled release: using hydrogel crosslinking chemistry to tune release of micro-crystalline active pharmaceutical ingredients
RSC Pharmaceutics·2024· 8 citedOpen Access
The motion of a self-propelling two-sphere swimmer in a weakly viscoelastic fluid
Journal of Non-Newtonian Fluid Mechanics·2024· 1 cited
Author response for "From Burst to Controlled Release: Using Hydrogel Crosslinking Chemistry to Tune Release of Micro-Crystalline Active Pharmaceutical Ingredients"
2024
Quantitative and spatially resolved detection of multiplexed microRNA from plant tissue via hybridization to hydrogel-bound DNA probes in nanoliter well arrays
Microsystems & Nanoengineering·2024· 2 citedOpen Access
QUANTITATIVE AND SPATIALLY RESOLVED DETECTION OF MULTIPLEXED MICRORNA FROM PLANT TISSUE USING NANOLITER WELL ARRAYS
2024Open Access
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Frequent Co-authors

T. Alan Hatton(8), Dhananjay Dendukuri(7), Stephen C. Chapin(6), Daniel C. Pregibon(4), Dae Kun Hwang(4), Mehmet Toner(3), Rathi L. Srinivas(3), Matthew E. Helgeson(3), David Appleyard(3), Liang Dai(3), Ankur Gupta(2), Hüseyin Burak Eral(2), Jean‐Louis Viovy(2), T. Alan Hatton(2), Priyadarshi Panda(2), Ramin Haghgooie(2), Kai P. Yuet(2), Greg C. Randall(2), Ki Wan Bong(2), Gareth H. McKinley(2)