Xian‐Ping Dong

Dalhousie University — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index5.6kcitations72works4.82yr avg
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Research Topics

Calcium signaling and nucleotide metabolism(41), Ion Channels and Receptors(15), Cellular transport and secretion(14), Adenosine and Purinergic Signaling(11), Ion channel regulation and function(9)

Publications72 total

Endosome–ER contact sites in phagophore formation
Trends in Cell Biology·2025
Targeting TRPML3 inhibits proliferation and invasion, and enhances doxorubicin sensitivity by disrupting lysosomal acidification and mitochondrial function in triple-negative breast cancer
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2025· 1 cited
Physiological and Pathological Functions of TRPML1
2024
MCOLN/TRPML channels in the regulation of MTORC1 and autophagy
Autophagy·2024· 18 citedOpen Access
TRPML3/BK complex promotes autophagy and bacterial clearance by providing a positive feedback regulation of mTOR via PI3P
Proceedings of the National Academy of Sciences·2023· 19 citedOpen Access
Proton-Activated Chloride Channel: Physiology and Disease
Frontiers in Bioscience-Landmark·2023· 4 citedOpen Access
Rapid screening of magnetic properties in several Fe-X-Ni systems via combinatorial materials chip method
Journal of Materiomics·2022· 5 citedOpen Access
Lysosomal ATP Transporter SLC17A9 Controls Cell Viability via Regulating Cathepsin D
Cells·2022· 7 citedOpen Access
Lysosomal potassium channels
Cell Calcium·2022· 19 cited
Lysosomal Potassium Channels
Handbook of experimental pharmacology·2022· 3 cited
Lysosomal Ion Channels and Human Diseases
2021
Lysosomal Calcium Channels in Autophagy and Cancer
Cancers·2021· 41 citedOpen Access
Endolysosomal TRPMLs in Cancer
Biomolecules·2021· 28 citedOpen Access
Multiple facets of TRPML1 in autophagy
Cell Calcium·2020· 23 cited
A lysosomal K+ channel regulates large particle phagocytosis by facilitating lysosome Ca2+ release
Scientific Reports·2020· 52 citedOpen Access
VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1
Nature Microbiology·2019· 106 citedOpen Access
Lysosomal Ca2+ release channel TRPML1 regulates lysosome size by promoting mTORC1 activity
European Journal of Cell Biology·2019· 20 cited
The lysosomal TRPML1 channel regulates triple negative breast cancer development by promoting mTORC1 and purinergic signaling pathways
Cell Calcium·2019· 60 cited
mTOR signalling: jack-of-all-trades
Biochemistry and Cell Biology·2018· 30 citedOpen Access
Engineering Pichia pastoris for Efficient Production of a Novel Bifunctional Strongylocentrotus purpuratus Invertebrate-Type Lysozyme
Applied Biochemistry and Biotechnology·2018· 7 cited
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Frequent Co-authors

Xi Zhong(13), Haoxing Xu(11), Qi Cao(10), Peng Huang(10), Xue Sun(8), Mengnan Xu(8), Dongbiao Shen(6), Xiping Cheng(6), Markus Delling(6), Wen‐Cheng Xiong(6), Lin Mei(5), Yuanjie Zou(5), Yi Yang(5), Xiaojuan Zhu(5), Xiang Wang(4), Eric Mills(4), Michael X. Zhu(4), Fudi Wang(3), David E. Clapham(3), Bin Zhang(3)