Manuela G. López

Hospital Universitario de La Princesa — Spain

Neuroscience · Life Sciences

62h-index15.8kcitations383works3.62yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(66), Ion channel regulation and function(63), Cholinesterase and Neurodegenerative Diseases(58), Nicotinic Acetylcholine Receptors Study(51), Chemical Synthesis and Analysis(50)

Publications378 total

Long-term Nrf2-driven microglial repopulation mitigates microgliosis, neuronal loss and cognitive deficits in tauopathy
2025
Targeting CB2 receptor with a novel antagonist reverses cognitive decline, neurodegeneration and pyroptosis in a TAU-dependent frontotemporal dementia mouse model
Brain Behavior and Immunity·2025· 4 cited
Health position paper and redox perspectives – Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases
Redox Biology·2025· 10 citedOpen Access
Corrigendum to “Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases” [Redox Biol. 79 (2025) 103464]
Redox Biology·2025Open Access
Unveiling the interplay between soluble guanylate cyclase activation and redox signalling in stroke pathophysiology and treatment
Biomedicine & Pharmacotherapy·2025· 2 citedOpen Access
Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases
Redox Biology·2024· 7 citedOpen Access
The mitochondrial Na+/Ca2+ exchanger NCLX is implied in the activation of hypoxia-inducible factors
Redox Biology·2024· 6 citedOpen Access
Discovery of a potent melatonin-based inhibitor of quinone reductase-2 with neuroprotective and neurogenic properties
European Journal of Medicinal Chemistry·2024· 3 citedOpen Access
The mitochondrial Na <sup>+</sup> /Ca <sup>2+</sup> exchanger NCLX is implied in the activation of hypoxia-inducible factors
2024Open Access
Reduction in Hippocampal Amyloid-β Peptide (Aβ) Content during Glycine-Proline-Glutamate (Gly-Pro-Glu) Co-Administration Is Associated with Changes in Inflammation and Insulin-like Growth Factor (IGF)-I Signaling
International Journal of Molecular Sciences·2024· 1 citedOpen Access
SCALABLE AND AFFORDABLE MANUFACTURE OF THERAPEUTIC MESENCHYMAL STROMAL CELL PRODUCTS ON CUSTOMIZABLE, DEGRADABLE MICROCARRIERS
Cytotherapy·2024
Innovative pathological network‐based multitarget approaches for Alzheimer's disease treatment
Medicinal Research Reviews·2024· 16 citedOpen Access
Reduction in Hippocampal Aβ Content During Gly-Pro-Glu Co-Administration Is Associated with Changes in Inflammation and IGF-I Signaling
Preprints.org·2024· 1 citedOpen Access
Discovery of a Potent Melatonin-Based Inhibitor of Quinone Reductase-2 with Neuroprotective and Neurogenic Properties
SSRN Electronic Journal·2024Open Access
Adipose tissue as a therapeutic target for vascular damage in Alzheimer's disease
British Journal of Pharmacology·2023· 14 citedOpen Access
Microglial Hemoxygenase-1 Deletion Reduces Inflammation in the Retina of Old Mice with Tauopathy
Antioxidants·2022· 3 citedOpen Access
Cytotoxicity Models in Chromaffin Cells to Evaluate Neuroprotective Compounds
Methods in molecular biology·2022
Changes in perinatal management and outcomes in infants born at 23 weeks of gestational age during the last decade in Spain
The Journal of Maternal-Fetal & Neonatal Medicine·2022· 5 cited
KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential
Medicinal Research Reviews·2022· 203 citedOpen Access
Small Synthetic Hyaluronan Disaccharide BIS014 Mitigates Neuropathic Pain in Mice
Journal of Pain·2022· 3 citedOpen Access
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Frequent Co-authors

Javier Egea(22), Antonio G. Garcı́a(20), Mércedes Villarroya(14), Antonio Cuadrado(12), Esther Parada(11), Izaskun Buendía(10), Rafael León(8), Alejandro Romero(7), Ana I. Casas(6), Elisa Navarro(6), Marı́a Isabel Rodrı́guez-Franco(6), Ana I. Rojo(5), Harald Schmidt(5), Concepción Pérez(4), Luis Gandı́a(4), Laura del Barrio(4), Ana Lúcia S. Rodrigues(4), José Marco‐Contelles(4), Pietro Ghezzi(3), Pablo Hernansanz‐Agustín(3)