Sergio Covarrubias

University of California, Santa Cruz — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index1.6kcitations44works4.02yr avg
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Research Topics

Cancer-related molecular mechanisms research(14), RNA modifications and cancer(14), RNA Research and Splicing(7), CRISPR and Genetic Engineering(6), Molecular Biology Techniques and Applications(6)

Publications44 total

CRISPRi Screen Identifies a Novel Growth Suppressor lncRNA, <i>INSTAR</i> , in Human Monocytes
2025Open Access
CRISPRi screen uncovers lncRNA regulators of human monocyte growth
Journal of Biological Chemistry·2025· 2 citedOpen Access
Human long noncoding RNA <i>VILMIR</i> is induced by major respiratory viral infections and modulates the host interferon response
Journal of Virology·2025· 7 citedOpen Access
CRISPRi Screen Uncovers lncRNA Regulators of Human Monocyte Growth
2024Open Access
Identification and functional characterization of lncRNAs involved in human monocyte-to-macrophage differentiation
RNA Biology·2024· 4 citedOpen Access
Identification and Functional Characterization of lncRNAs involved in Human Monocyte-to-Macrophage Differentiation
2024· 1 citedOpen Access
CRISPRi screens identify the lncRNA, <i>LOUP</i> , as a multifunctional locus regulating macrophage differentiation and inflammatory signaling
Proceedings of the National Academy of Sciences·2024· 18 citedOpen Access
Human long noncoding RNA, <i>VILMIR,</i> is induced by major respiratory viral infections and modulates the host interferon response
2024· 1 citedOpen Access
New Genetic Variants of RUNX2 in Mexican Families Cause Cleidocranial Dysplasia
Biology·2024· 5 citedOpen Access
New Genetic Variants of RUNX2 in Mexican Families Causes Cleidocranial Dysplasia
Preprints.org·2024· 2 citedOpen Access
CRISPRi screens identify the lncRNA, <i>LOUP,</i> as a multifunctional locus regulating macrophage differentiation epigenetically and inflammatory signaling through a short, encoded peptide
2023Open Access
Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of Aim2
eLife·2021· 43 citedOpen Access
Author response: Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of Aim2
2021Open Access
Generation and utilization of a HEK-293T murine GM-CSF expressing cell line
PLoS ONE·2021· 5 citedOpen Access
A conserved long noncoding RNA, GAPLINC, modulates the immune response during endotoxic shock
Proceedings of the National Academy of Sciences·2021· 45 citedOpen Access
M2 macrophage exosomes regulate hematopoiesis &amp; resolve inflammation in atherosclerosis via microrna cargo
Atherosclerosis·2020· 2 cited
High-Throughput CRISPR Screening Identifies Genes Involved in Macrophage Viability and Inflammatory Pathways
Cell Reports·2020· 54 citedOpen Access
Generation and utilization of a HEK-293T murine GM-CSF expressing cell line v1
2020· 1 citedOpen Access
Inflammation Drives Alternative First Exon usage to Regulate Immune Genes including a Novel Iron Regulated Isoform of Aim2
2020· 6 citedOpen Access
Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo
Cell Reports·2020· 237 citedOpen Access
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Frequent Co-authors

Susan Carpenter(22), Michael T. McManus(15), Elektra K. Robinson(12), Sol Katzman(11), Michael Boettcher(9), James Blau(9), Anne Biton(7), Haopeng Wang(7), Noah Zaitlen(7), Eric Malekos(7), Christy Montano(7), Barbara Shapleigh(5), Lisa Sudek(5), Susan Carpenter(4), Allyson Capili(4), Britt A. Glaunsinger(4), Apple Cortez Vollmers(4), Haley Halasz(3), Christopher Vollmers(3), Pratibha Jagannatha(3)