Charles A. Parkos

University of Michigan–Ann Arbor — United States

Medicine · Health Sciences

84h-index24.0kcitations411works2.52yr avg
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Research Topics

Cell Adhesion Molecules Research(119), Barrier Structure and Function Studies(91), Immune Response and Inflammation(80), Wnt/β-catenin signaling in development and cancer(40), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(39)

Publications410 total

RUNX2 promotes epigenetic WNT signaling in inflamed intestinal epithelial cells
2025Open Access
Barrier function facilitates cross-talk between skin and intestine in a model of food allergy 3054
The Journal of Immunology·2025Open Access
CRB3 and NF2 orchestrate cytoskeletal dynamics to control epithelial barrier assembly
JCI Insight·2025Open Access
1144: THE ROLE OF EPITHELIAL LTB4/BLT1 SIGNALING IN RESOLUTION OF COLONIC MUCOSAL WOUNDS
Gastroenterology·2025
Crb3 and NF2: A dynamic duo that controls assembly of the apical junctions and barrier function via Rho/ROCK signaling
2025Open Access
STARD7 maintains intestinal epithelial mitochondria architecture, barrier integrity, and protection from colitis
JCI Insight·2024· 10 citedOpen Access
Interferon‐gamma signaling drives epithelial <scp>TNF</scp> ‐alpha receptor‐2 expression during colonic tissue repair
The FASEB Journal·2024· 4 citedOpen Access
The human CD47 checkpoint is targeted by an immunosuppressive <i>Aedes aegypti</i> salivary factor to enhance arboviral skin infectivity
Science Immunology·2024· 4 citedOpen Access
Critical role of thrombospondin-1 in promoting intestinal mucosal wound repair
JCI Insight·2024· 14 citedOpen Access
Allergen‐Encapsulating Nanoparticles Reprogram Pathogenic Allergen‐Specific Th2 Cells to Suppress Food Allergy
Advanced Healthcare Materials·2024· 10 citedOpen Access
Tu1491 SIALYLATION OF THE β2 INTEGRIN CD11B/CD18 REGULATES NEUTROPHIL TRAFFICKING AND INFLAMMATORY FUNCTION IN THE INTESTINE
Gastroenterology·2024
CD11B/CD18 SIALYLATION REGULATES NEUTROPHIL TRAFFICKING AND INFLAMMATORY FUNCTION IN THE INTESTINE
Gastroenterology·2024Open Access
CD11B/CD18 SIALYLATION REGULATES NEUTROPHIL TRAFFICKING AND INFLAMMATORY FUNCTION IN THE INTESTINE
Inflammatory Bowel Diseases·2024· 1 citedOpen Access
INFLAMMATION-TRIGGERED CLAUDIN-23 DOWNREGULATION IMPACTS INTESTINAL EPITHELIAL BARRIER FUNCTION
Inflammatory Bowel Diseases·2024Open Access
INFLAMMATION-TRIGGERED CLAUDIN-23 DOWNREGULATION IMPACTS INTESTINAL EPITHELIAL BARRIER FUNCTION
Gastroenterology·2024Open Access
NANOPARTICLE ENCAPSULATION OF THE SPECIALIZED PRO-RESOLVING MEDIATOR MARESIN-2: A NOVEL APPROACH FOR PROMOTING MUCOSAL REPAIR IN THE INTESTINE
Gastroenterology·2024Open Access
NANOPARTICLE ENCAPSULATION OF THE SPECIALIZED PRO-RESOLVING MEDIATOR MARESIN-2: A NOVEL APPROACH FOR PROMOTING MUCOSAL REPAIR IN THE INTESTINE
Inflammatory Bowel Diseases·2024Open Access
Claudin-23 reshapes epithelial tight junction architecture to regulate barrier function
Nature Communications·2023· 61 citedOpen Access
CXADR-Like Membrane Protein Regulates Colonic Epithelial Cell Proliferation and Prevents Tumor Growth
Gastroenterology·2023· 8 citedOpen Access
342 SIALYLATION REGULATES NEUTROPHIL TRANSEPITHELIAL MIGRATION, CD11B/CD18 ACTIVATION AND MUCOSAL INFLAMMATORY FUNCTION IN THE GUT
Gastroenterology·2023
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Frequent Co-authors

Asma Nusrat(25), James Madara(11), Andrei I. Ivanov(9), Asma Nusrat(7), Brian A. Babbin(6), Winston Y. Lee(4), Algirdas J. Jesaitis(4), Ke Zen(4), Matthias Bruewer(3), Ann M. Hopkins(3), Frederick J. Schnell(3), Christopher Capaldo(3), Ifor R. Williams(3), Jerrold R. Turner(3), Giovanna Leoni(3), Miguel Quirós(3), Roland Hilgarth(3), Mauro Perretti(3), Andrew S. Neish(3), Markus Utech(3)