William A. Bridger

Medical Council of Canada — Canada

Materials Science · Physical Sciences

25h-index1.6kcitations66works0.02yr avg
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Research Topics

Enzyme Structure and Function(24), Biochemical and Molecular Research(17), Microbial Metabolic Engineering and Bioproduction(15), Metabolism and Genetic Disorders(14), Mitochondrial Function and Pathology(10)

Publications66 total

Pig Heart CoA Transferase Exists as Two Oligomeric Forms Separated by a Large Kinetic Barrier
Biochemistry·2000· 17 cited
Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase
Journal of Molecular Biology·2000· 54 cited
ADP-Binding Site of <i>Escherichia coli</i> Succinyl-CoA Synthetase Revealed by X-ray Crystallography<sup>,</sup>
Biochemistry·1999· 56 cited
Probing the Nucleotide-Binding Site of <i>Escherichia coli</i> Succinyl-CoA Synthetase
Biochemistry·1999· 33 cited
A detailed structural description of Escherichia coli succinly-CoA synthetase
Journal of Molecular Biology·1999· 84 cited
A detailed structural description of Escherichia coli succinyl-CoA synthetase
Journal of Molecular Biology·1999· 88 cited
A dimeric form of Escherichia coli succinyl-CoA synthetase produced by site-directed mutagenesis 1 1Edited by D. Rees
Journal of Molecular Biology·1999· 21 cited
Mutually Exclusive Splicing Generates Two Distinct Isoforms of Pig Heart Succinyl-CoA Synthetase
Journal of Biological Chemistry·1997· 14 citedOpen Access
Productive Interactions between the Two Domains of Pig Heart CoA Transferase during Folding and Assembly
Biochemistry·1997· 8 cited
Identification of glutamate 344 as the catalytic residue in the active site of pig heart CoA transferase
Protein Science·1994· 39 citedOpen Access
The crystal structure of succinyl-CoA synthetase from Escherichia coli at 2.5-A resolution.
Journal of Biological Chemistry·1994· 123 citedOpen Access
Identification of the active site of CoA transferase by peptide sequencing
Peptides·1994· 1 cited
Cloning, characterization, and expression of the β subunit of pig heart succinyl‐CoA synthetase
Protein Science·1993· 18 citedOpen Access
Folding and assembly of the Escherichia coli succinyl-CoA synthetase heterotetramer without participation of molecular chaperones
Biochemistry·1992· 3 cited
Sequence of a cDNA clone encoding pig heart mitochondrial CoA transferase.
Journal of Biological Chemistry·1992· 29 citedOpen Access
Bacterial expression of rat liver succinyl-CoA synthetase α-subunit
Journal of Molecular Biology·1991· 4 cited
Functional consequences of substitution of the active site (phospho)histidine residue of Escherichia coli succinyl-CoA synthetase
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology·1991· 21 cited
Mitochondrial translocation and processing of the precursor to the α-subunit of rat liver succinyl-CoA synthetase
Biochemistry and Cell Biology·1990· 7 cited
Assembly and Catalytic Functions of the Subunits of Succinyl Coenzyme A Synthetase
1988
Phosphorylation by cyclic AMP‐dependent protein kinase does not affect the association of ATP citrate‐lyase with isolated mitochondria
FEBS Letters·1987
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Frequent Co-authors

William T. Wolodko(18), M.E. Fraser(8), Michael N.G. James(8), Hans J. Vogel(6), Edward R. Brownie(6), Anita Krebs(3), Howard Engers(3), Neil B. Madsen(3), Jean‐Christophe Rochet(3), Frank J. Moffet(3), Cyril M. Kay(3), Ramanath Majumdar(3), Michael Joyce(2), Leonard Cohen(2), Brian D. Sykes(2), W Paranchych(2), Susan P. Williams(2), M D O'Connor(2), Bengt R. Osterlund(2), Darrin L. Bailey(2)