Ivan da Rocha Pitta

Universidade Federal de Pernambuco — Brazil

Chemistry · Physical Sciences

31h-index3.4kcitations252works1.02yr avg
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Research Topics

Synthesis and biological activity(60), Peroxisome Proliferator-Activated Receptors(32), Synthesis of heterocyclic compounds(28), Synthesis and Characterization of Heterocyclic Compounds(23), Synthesis and Reactivity of Sulfur-Containing Compounds(21)

Publications252 total

Evaluation of Thiazolidine Derivatives with Potential Anti-ZIKV Activity
Current Topics in Medicinal Chemistry·2024· 2 cited
Antidepressant effect of PT-31, an α₂-adrenoceptor agonist, on lipopolysaccharide-induced depressive-like behavior in mice
Behavioural Pharmacology·2024
Synthesis and In vitro and In silico Anti-inflammatory Activity of NewThiazolidinedione-quinoline Derivatives
Current Topics in Medicinal Chemistry·2024· 1 cited
PPARγ partial agonist LPSF/GQ-16 prevents dermal and pulmonary fibrosis in HOCl-induced systemic sclerosis (SSc) and modulates cytokine production in PBMC of SSc patients
Inflammopharmacology·2023· 5 cited
Genotoxic and Mutagenic Assessment of PT-31, a Molecule withAntipsychotic Potential
Drug Delivery Letters·2023
High serum levels of galectins 1 and 4 in osteoarthritis patients
Clinical Biochemistry·2023· 3 cited
Cytotoxicity evaluation of haloperidol, clozapine and a new molecule with antipsychotic potential, PT-31, in NIH-3T3 cells
Figshare·2023Open Access
Cytotoxicity evaluation of haloperidol, clozapine and a new molecule with antipsychotic potential, PT-31, in NIH-3T3 cells
Brazilian Journal of Pharmaceutical Sciences·2023· 1 citedOpen Access
Vitamin D Presented In Vitro Immunomodulatory Property on T Lymphocyte-Related Cytokines in Systemic Lupus Erythematosus
Inflammation·2022· 3 cited
In vitro and in vivo profile of PT-31 GIRSUPAN, a novel α2-adrenoceptor agonist with analgesic properties
Research Square (Research Square)·2022Open Access
Study of the acute and repeated dose 28-day oral toxicity in mice treated with PT-31, a molecule with a potential antipsychotic profile
Toxicology Mechanisms and Methods·2022· 2 cited
Synthesis, Assessment of Antineoplastic Activity, and Molecular Dockingof Novel 2-Thioxo-oxazolidin-4-one Derivatives
Medicinal Chemistry·2022· 1 cited
SÍNTESE, CARACTERIZAÇÃO E ATIVIDADE BIOLÓGICA DO DERIVADO TIAZACRIDÍNICO LPSF/AA-57
2022
Ischemia-Reperfusion Damage is Attenuated by GQ-11, A Peroxisome Proliferator-Activated Receptor (PPAR)-α/γ Agonist, after Aorta Clamping in Rats
SSRN Electronic Journal·2022Open Access
Análise do Mercado de Oncológicos e Novas Substância Ativas para o Tratamento do Câncer / Oncology Market Analysis and New Active Substances for Cancer Treatment
Brazilian Journal of Development·2021· 1 citedOpen Access
Synthesis of novel thiazolidinic-phthalimide derivatives evaluated as new multi-target antiepileptic agents
Bioorganic Chemistry·2021· 15 cited
Synthesis and biological activities of new phthalimide and thiazolidine derivatives
Medicinal Chemistry Research·2021· 7 cited
Evaluation of the action of LPSF/GQ-16 on cytokines and PPAR-γ gene expression after in vitro irradiation of peripheral blood mononuclear cells
International Journal of Radiation Biology·2021· 1 cited
Polylactide Nanocapsules Attenuate Adverse Cardiac Cellular Effects of Lyso-7, a Pan-PPAR Agonist/Anti-Inflammatory New Thiazolidinedione
Pharmaceutics·2021· 6 citedOpen Access
Design, Synthesis and Biological Activities of New Phthalimide and Thiazolidine Derivatives
Research Square (Research Square)·2021· 1 citedOpen Access
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Frequent Co-authors

Suely Lins Galdino(24), Maria do Carmo Alves de Lima(24), Maíra Galdino da Rocha Pitta(22), Moacyr Jesus Barreto de Melo Rêgo(19), Ângela Luzia Branco Pinto Duarte(15), Michelly Cristiny Pereira(13), Andréa Tavares Dantas(10), Marcelo Zaldini Hernandes(10), Marina Galdino da Rocha Pitta(10), Cláudia Diniz Lopes Marques(9), Laurindo Ferreira da Rocha(5), Sayonara Maria Calado Gonçalves(5), Priscilla Stela Santana de Oliveira(4), Dulcinéia Saes Parra Abdalla(4), Francisco de Assis Rocha Neves(4), Teresinha Gonçalves da Silva(4), Francisco Jaime Bezerra Mendonça(4), Ricardo Olímpio de Moura(4), Anderson Rodrigues de Almeida(4), Angélica Amorim Amato(3)