Benjamin E. Gewurz

Broad Institute — United States

Medicine · Health Sciences

44h-index6.6kcitations155works2.82yr avg
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Research Topics

Viral-associated cancers and disorders(73), Immune Cell Function and Interaction(38), Cytomegalovirus and herpesvirus research(37), Lymphoma Diagnosis and Treatment(30), Cancer Immunotherapy and Biomarkers(22)

Publications154 total

Integrated transcriptomic and methylome analysis reveals retinoic acid pathway activation after decitabine treatment in EBV-associated gastric cancer
mBio·2026Open Access
EBNA1 INHIBITORS REVEAL CDC7 AND POU2F1 AS DIRECT FUNCTIONAL TARGETS IN EBV EPITHELIAL CANCERS
2026Open Access
Epstein-barr virus latent membrane protein 1 targets cIAP1, cIAP2 and TRAF2 for proteasomal degradation to activate the non-canonical NF-κB pathway
PLoS Pathogens·2026Open Access
A tonsil organoid model reveals Epstein-Barr virus infected germinal center B cell states during primary infection
2026Open Access
P-2180. Evaluation of Cytomegalovirus Resistance at an Academic Medical Center
Open Forum Infectious Diseases·2026Open Access
The CTLH ubiquitin ligase substrates ZMYND19 and MKLN1 negatively regulate mTORC1 at the lysosomal membrane
Nature Communications·2025Open Access
EBV infection and immune response dynamics in human tonsil organoids 4366
The Journal of Immunology·2025Open Access
Lysine-specific histone demethylase complex restricts Epstein–Barr virus lytic reactivation
Nature Microbiology·2025· 1 cited
Epstein-Barr Virus Encoded lncRNAs Control the Viral Lytic Switch
2025Open Access
Arginine Metabolism Supports <i>De Novo</i> Pyrimidine Biosynthesis to Block DNA Damage and Maintain Epstein-Barr Virus Latency
2025Open Access
Integrated transcriptomic and methylome analysis reveals retinoic acid pathway activation after decitabine treatment in EBV associated gastric cancer
2025Open Access
Epstein–Barr virus exploits desmocollin 2 as the principal epithelial cell entry receptor
Nature Microbiology·2025· 1 cited
Multiomic analysis reveals a key BCAT1 role in mTOR activation by B cell receptor and TLR9
Journal of Clinical Investigation·2025Open Access
Epstein-Barr Virus Latent Membrane Protein 1 targets cIAP1, cIAP2 and TRAF2 for Proteasomal Degradation to Activate the Non-canonical NF-κB Pathway
2025Open Access
MUC1-C auto-regulatory complex with EBNA1 is responsible for latent Epstein-Barr virus-associated gastric cancer progression
Oncogene·2025· 2 citedOpen Access
Systematic investigation reveals extensive Epstein-Barr virus transcriptional regulation of the human genome
2025· 2 citedOpen Access
Insights into absence of lymphoma despite fulminant Epstein-Barr virus infection in patients with XIAP deficiency
JCI Insight·2025Open Access
A multi-omics resource of B cell activation reveals genetic mechanisms for immune-mediated diseases
2025· 1 citedOpen Access
Epstein-Barr virus latent membrane protein 1 subverts IMPDH pathways to drive B-cell oncometabolism
PLoS Pathogens·2025· 2 citedOpen Access
TGFβ links EBV to multisystem inflammatory syndrome in children
Nature·2025· 23 citedOpen Access
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Frequent Co-authors

Bo Zhao(20), Elliott Kieff(12), Rui Guo(11), Sizun Jiang(9), Yijie Ma(8), Stephen J. Trudeau(7), Liang Wei Wang(6), Ina Ersing(6), Hufeng Zhou(6), Chang Jiang(6), Domenico Tortorella(5), Hidde L. Ploegh(5), Michael P. Weekes(5), Kaoru Takasaki(5), John G. Doench(5), Yuchen Zhang(5), Mingxiang Teng(5), Qian Zhong(4), Ellen Cahir-McFarland(4), Katharina Bernhardt(4)