Martin J. Lercher

Steinbeis Foundation — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

55h-index14.8kcitations187works8.92yr avg
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Research Topics

Microbial Metabolic Engineering and Bioproduction(48), Genomics and Phylogenetic Studies(44), Bioinformatics and Genomic Networks(25), Protein Structure and Dynamics(23), RNA and protein synthesis mechanisms(22)

Publications187 total

Predicting turnover number fold-changes to recover true mutation effects and overcome biases in mutant datasets
2026Open Access
FoldVision: A compute-efficient atom-level 3D protein encoder
2026Open Access
How optimal protein production led to understanding bacterial genome organization
2025
The fate of horizontally acquired genes: rapid initial turnover followed by long-term persistence
2025· 1 citedOpen Access
Horizontal Gene Transfer Inference: Gene Presence–Absence Outperforms Gene Trees
Molecular Biology and Evolution·2025· 4 citedOpen Access
Growth Mechanics and the emergence of metabolic oscillations in growing cells
2025Open Access
DeepMolecules: a web server for predicting enzyme and transporter–small molecule interactions
Nucleic Acids Research·2025· 7 citedOpen Access
Most bacterial gene families are biased toward specific chromosomal positions
Science·2025· 14 cited
Openness guides discovery
Nature Biotechnology·2025· 1 cited
Most bacterial gene families are biased toward specific chromosomal positions
Zenodo (CERN European Organization for Nuclear Research)·2025Open Access
Streamlined genomes, not horizontal gene transfer, mark bacterial transitions to unfamiliar environments
2024· 2 citedOpen Access
Horizontal Gene Transfer Inference: Gene presence-absence outperforms gene trees
2024· 1 cited
SPOT: A machine learning model that predicts specific substrates for transport proteins
PLoS Biology·2024· 13 citedOpen Access
Teach creativity in science higher education
Science·2024· 3 cited
A multimodal Transformer Network for protein-small molecule interactions enhances predictions of kinase inhibition and enzyme-substrate relationships
PLoS Computational Biology·2024· 24 citedOpen Access
Sugar transporters spatially organize microbiota colonization along the longitudinal root axis of Arabidopsis
Cell Host & Microbe·2024· 53 citedOpen Access
DLKcat cannot predict meaningful <i>k</i>cat values for mutants and unfamiliar enzymes
Biology Methods and Protocols·2024· 24 citedOpen Access
It takes two to think
Nature Biotechnology·2024· 14 cited
Thinking about science <b>I’ve Been Thinking</b> <i>Daniel C. Dennett</i> Norton, 2023. 464 pp.
Science·2023
A general prediction model for substrates of transport proteins
2023· 4 citedOpen Access
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Frequent Co-authors

Laurence D. Hurst(9), Wei‐Hua Chen(7), Csaba Pál(7), Balázs Papp(6), Songnian Hu(5), Andreas P.M. Weber(5), Peer Bork(5), David Heckmann(4), Shenghan Gao(3), Andrea Bräutigam(3), K. Wienhard(3), Christian von Mering(3), Udo Gowik(3), Peter Westhoff(3), Abdelmoneim Amer Desouki(3), Balázs Szappanos(3), Gabriel Gelius‐Dietrich(3), Alexander Kroll(3), Claus Jonathan Fritzemeier(3), Huangkai Zhang(2)