David R. Spring

University of Cambridge — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

67h-index20.3kcitations539works3.32yr avg
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Research Topics

Chemical Synthesis and Analysis(147), Click Chemistry and Applications(71), Crystallization and Solubility Studies(64), X-ray Diffraction in Crystallography(64), Synthetic Organic Chemistry Methods(46)

Publications539 total

Bismuth Bicycles
Journal of Peptide Science·2026Open Access
Targeting a Pleckstrin Homology Domain with a Lysine-Reactive Covalent Binder
2025Open Access
An allantoin-inducible glyoxylate utilization pathway in Pseudomonas aeruginosa
Microbiology·2025Open Access
MMP-cleavable linker platform for tumour-responsive homo- and heterobivalent antibody–drug conjugates
Chemical Science·2025Open Access
Bismuth Bicycles.
Apollo (University of Cambridge)·2025
Exploiting the Cryptic αD Pocket of Casein Kinase 2α (CK2α) to Deliver Highly Potent and Selective Type 1 Inhibitors
Journal of Medicinal Chemistry·2025· 1 citedOpen Access
Author response: Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome
2025Open Access
Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome
eLife·2025Open Access
A Dynamic Silver(I) Nanocluster Holds Together a 3 × 3 Self-Assembled Grid
Journal of the American Chemical Society·2025Open Access
Author response: Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
2025Open Access
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
2025Open Access
Methods for the Generation of Single‐Payload Antibody‐Drug Conjugates
ChemMedChem·2025· 6 citedOpen Access
Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity
Nature Communications·2025· 11 citedOpen Access
Pseudomonas aeruginosa PfpI is a methylglyoxalase
Journal of Biological Chemistry·2025· 2 citedOpen Access
The 2-methylcitrate cycle and the glyoxylate shunt in Pseudomonas aeruginosa are linked through enzymatic redundancy
Journal of Biological Chemistry·2025· 5 citedOpen Access
Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome
eLife·2025· 3 citedOpen Access
Author response: Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
2025Open Access
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
2025Open Access
Advances in the Release of Amide‐Containing Molecules
Chemistry - A European Journal·2025· 2 citedOpen Access
A platform for SpyCatcher conjugation to native antibodies
Chemical Science·2025· 1 citedOpen Access
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Frequent Co-authors

Warren R. J. D. Galloway(10), Zhaochao Xu(9), Martin Welch(9), Juyoung Yoon(6), Andreas Bender(6), Albert Isidro‐Llobet(4), Jingnan Cui(4), James T. Hodgkinson(4), Hannah F. Sore(4), Yu Heng Lau(3), Peterson de Andrade(3), Jeremy S. Parker(3), George P. C. Salmond(3), Stephen J. Walsh(3), Richard J. Spandl(3), Stuart L. Schreiber(3), Luca Laraia(3), Marko Hyvönen(3), Ashok R. Venkitaraman(3), Gemma L. Thomas(3)