Luisa Salter–Cid

Pioneer (United States) — United States

Medicine · Health Sciences

37h-index3.8kcitations127works3.02yr avg
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Research Topics

Cytokine Signaling Pathways and Interactions(19), Crystallization and Solubility Studies(19), X-ray Diffraction in Crystallography(19), T-cell and B-cell Immunology(13), Immune Response and Inflammation(11)

Publications127 total

A long-acting high affinity anti-TSLP antibody (GB-0895) for severe asthma identified leveraging a proprietary machine learning platform
2024· 3 cited
1378 Discovery and characterization of PM-4321, a selective inhibitor of the aryl hydrocarbon receptor (AHR) with anti-tumor immunomodulatory effects
Regular and Young Investigator Award Abstracts·2023Open Access
Inhaled seralutinib exhibits potent efficacy in models of pulmonary arterial hypertension
European Respiratory Journal·2022· 64 citedOpen Access
Identification of 2-Pyridinylindole-Based Dual Antagonists of Toll-like Receptors 7 and 8 (TLR7/8)
ACS Medicinal Chemistry Letters·2022· 13 citedOpen Access
CCDC 1501156: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
CCDC 1501157: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
Mouse IL-2/CD25 Fusion Protein Induces Regulatory T Cell Expansion and Immune Suppression in Preclinical Models of Systemic Lupus Erythematosus
The Journal of Immunology·2021· 22 cited
Correction: RORγt Represses IL-10 Production in Th17 Cells To Maintain Their Pathogenicity in Inducing Intestinal Inflammation
The Journal of Immunology·2021· 4 citedOpen Access
P059 GB004 drives protective effects on immune cells and epithelial cells using human ex vivo monolayer and co-culture systems
Journal of Crohn s and Colitis·2021· 3 citedOpen Access
Fr150 GB004 EXHIBITS PROTECTIVE EFFECTS DIRECTLY ON EPITHELIAL CELLS USING EX VIVO ORGANOID AND MONOLAYER CULTURES
Gastroenterology·2021· 2 cited
Tricyclic-Carbocyclic RORγt Inverse Agonists—Discovery of BMS-986313
Journal of Medicinal Chemistry·2021· 15 citedOpen Access
Bicyclic Ligand-Biased Agonists of S1P<sub>1</sub>: Exploring Side Chain Modifications to Modulate the PK, PD, and Safety Profiles
Journal of Medicinal Chemistry·2021· 5 citedOpen Access
Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor
Journal for ImmunoTherapy of Cancer·2021· 75 citedOpen Access
Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches
Journal of Medicinal Chemistry·2020· 39 citedOpen Access
Novel Tricyclic Pyroglutamide Derivatives as Potent RORγt Inverse Agonists Identified using a Virtual Screening Approach
ACS Medicinal Chemistry Letters·2020· 16 citedOpen Access
Driving Potency with Rotationally Stable Atropisomers: Discovery of Pyridopyrimidinedione-Carbazole Inhibitors of BTK
ACS Medicinal Chemistry Letters·2020· 9 citedOpen Access
GB001 potently inhibits PGD2 metabolite-induced DP2-mediated cell signaling and eosinophil activation
2020· 1 cited
Pharmacologic characterization of GB002, a novel inhaled PDGFR kinase inhibitor in development for pulmonary arterial hypertension (PAH)
2020· 1 cited
GB001 is a potent, insurmountable DP2 antagonist with long receptor residence time and extended pharmacodynamic effects
2020
Tricyclic sulfones as potent, selective and efficacious RORγt inverse agonists – Exploring C6 and C8 SAR using late-stage functionalization
Bioorganic & Medicinal Chemistry Letters·2020· 4 citedOpen Access
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Frequent Co-authors

Percy H. Carter(12), Kim W. McIntyre(11), Jenny Xie(11), Martin F. Flajnik(11), Joel C. Barrish(9), Kathleen M. Gillooly(8), Celia D’Arienzo(8), Dauh‐Rurng Wu(8), David J. Shuster(8), T. G. Murali Dhar(8), James R. Burke(7), Arvind Mathur(7), Aberra Fura(7), John S. Sack(7), James J.‐W. Duan(7), Qihong Zhao(6), Joseph A. Tino(6), Virna Borowski(6), Javed Khan(6), Lihong Cheng(5)