Norbert Klugbauer

University of Freiburg — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

45h-index8.6kcitations113works5.32yr avg
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Research Topics

Ion channel regulation and function(68), Cardiac electrophysiology and arrhythmias(46), Neuroscience and Neuropharmacology Research(39), Nicotinic Acetylcholine Receptors Study(16), Calcium signaling and nucleotide metabolism(14)

Publications112 total

Small molecule agonist TPC2-A1-N increases intracellular Ca2+ independent of two-pore channels
Journal of Biological Chemistry·2025Open Access
The Human‐Specific <scp>miR</scp>‐6762‐5p Is an Activator of <scp>RhoA GTPase</scp> Enhancing <scp><i>Shigella flexneri</i></scp> Intercellular Spreading
Molecular Microbiology·2025· 2 citedOpen Access
OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage
Journal of Clinical Investigation·2024· 14 citedOpen Access
Englerin A Inhibits T-Type Voltage-Gated Calcium Channels at Low Micromolar Concentrations
Molecular Pharmacology·2023· 1 citedOpen Access
Two‐pore channel protein <scp>TPC1</scp> is a determining factor for the adaptation of proximal tubular phosphate handling
Acta Physiologica·2023· 5 citedOpen Access
The human-specific miR-6762-5p is an activator of RhoA GTPase enhancing <i>Shigella flexneri</i> intercellular spreading
2022· 1 cited
Genome wide CRISPR screen for <i>Pasteurella multocida</i> toxin (PMT) binding proteins reveals LDL Receptor Related Protein1 (LRP1) as crucial cellular receptor
2022· 3 citedOpen Access
Two-Pore Channels Regulate Expression of Various Receptors and Their Pathway-Related Proteins in Multiple Ways
Cells·2021· 4 citedOpen Access
TPC2 promotes choroidal angiogenesis and inflammation in a mouse model of neovascular age-related macular degeneration
Life Science Alliance·2021· 18 citedOpen Access
Two-pore channels affect EGF receptor signaling by receptor trafficking and expression
iScience·2021· 10 citedOpen Access
Genetic Inactivation of Two-Pore Channel 1 Impairs Spatial Learning and Memory
Behavior Genetics·2020· 10 citedOpen Access
TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity
Proceedings of the National Academy of Sciences·2020· 35 citedOpen Access
Modulation of voltage-gated Ca<sub>V</sub>2.2 Ca<sup>2+</sup> channels by newly identified interaction partners
Channels·2020· 5 citedOpen Access
High-Resolution Complexome Profiling by Cryoslicing BN-MS Analysis
Journal of Visualized Experiments·2019· 13 cited
High-Resolution Complexome Profiling by Cryoslicing BN-MS Analysis
Journal of Visualized Experiments·2019· 2 citedOpen Access
Spatiotemporal Role of Transforming Growth Factor Beta 2 in Developing and Mature Mouse Hindbrain Serotonergic Neurons
Frontiers in Cellular Neuroscience·2019· 5 citedOpen Access
Grina/TMBIM3 modulates voltage-gated CaV2.2 Ca2+ channels in a G-protein-like manner
Cell Calcium·2019· 7 cited
Spatiotemporal Role of Transforming Growth Factor Beta 2 in Developing and Mature Mouse Hindbrain Serotonergic Neurons
The FASEB Journal·2019
Correction to: Four novel interaction partners demonstrate diverse modulatory effects on voltage-gated CaV2.2 Ca2+ channels
Pflügers Archiv - European Journal of Physiology·2019Open Access
Four novel interaction partners demonstrate diverse modulatory effects on voltage-gated CaV2.2 Ca2+ channels
Pflügers Archiv - European Journal of Physiology·2019· 7 cited
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Frequent Co-authors

Franz Hofmann(33), Ľubica Lacinová(12), Elsé Marais(7), Martin Biel(5), Andrea Welling(5), Wolfgang Ludwig(4), Christian Wahl‐Schott(4), Sven Moosmang(4), Verena Schulla(4), Robert Feil(4), Shuiping Dai(4), Jan Castonguay(4), Michael Weizenegger(3), Marianne Bachleitner(3), Christian Grimm(3), Thomas Kleppisch(3), Veit Flockerzi(3), Jörg W. Wegener(3), Angela Koller(3), Karel Talavera(3)