Mark D. Gorrell

University of Sydney — Australia

Medicine · Health Sciences

50h-index8.7kcitations213works3.82yr avg
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Research Topics

Peptidase Inhibition and Analysis(109), Neuropeptides and Animal Physiology(57), Liver Disease Diagnosis and Treatment(37), Diabetes Treatment and Management(33), Protease and Inhibitor Mechanisms(30)

Publications212 total

Disease-associated genetic variants can cause mutations in tissue-specific protein isoforms
2025· 1 citedOpen Access
Dipeptidyl peptidase 9 (DPP9) depletion from hepatocytes in mice to retard tumour growth, increase intrahepatic caspase-1 activation, and alter metabolic markers.
Journal of Clinical Oncology·2025· 1 cited
Development of a Protocol for Long‐Term Ex Vivo Normothermic Machine Perfusion of Rodent Livers
Artificial Organs·2025Open Access
The multifunctional regulatory post-proline protease dipeptidyl peptidase 9 and its inhibitors: new opportunities for therapeutics
Cellular and Molecular Life Sciences·2025· 4 citedOpen Access
Dipeptidyl peptidase 9 (DPP9) depletion from hepatocytes in experimental primary liver cancer
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2025· 3 citedOpen Access
The Role of Sphingolipids in NASH Progression Revealed by Lipidomics
Obesity Research & Clinical Practice·2024
Long-term ex situ normothermic machine perfusion allows regeneration of human livers with severe bile duct injury
American Journal of Transplantation·2024· 10 citedOpen Access
Development and validation of a novel circulating fibroblast activation protein - based predictive model to improve fibrosis risk stratification in metabolic liver disease population
2024Open Access
WED-267 The FAP Index: A statistical model aiding the detection of advanced liver fibrosis in people with diabetes, obesity or metabolic dysfunction-associated steatosis using a marker of activated stellate cells and myofibroblasts
Journal of Hepatology·2024
Dipeptidyl Peptidase 9 (DPP9) Depletion From Hepatocytes in Mice Retards Liver Tumour Growth and Increases Intrahepatic Caspase-1 Activation
Preprints.org·2024Open Access
Bile acids mediate fructose-associated liver tumour growth in mice
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2024· 3 citedOpen Access
Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis
Journal of Translational Medicine·2024· 23 citedOpen Access
Application and Diagnostic Performance of Two-Dimensional Shear Wave Elastography and Liver Fibrosis Scores in Adults with Class 3 Obesity
Nutrients·2023· 11 citedOpen Access
Faculty Opinions recommendation of Current progress of pig models for liver cancer research.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2023
Supplementary Figures S1-S4 from A Novel Role of Dipeptidyl Peptidase 9 in Epidermal Growth Factor Signaling
2023Open Access
Data from A Novel Role of Dipeptidyl Peptidase 9 in Epidermal Growth Factor Signaling
2023Open Access
Data from A Novel Role of Dipeptidyl Peptidase 9 in Epidermal Growth Factor Signaling
2023Open Access
Supplementary Figures S1-S4 from A Novel Role of Dipeptidyl Peptidase 9 in Epidermal Growth Factor Signaling
2023Open Access
Faculty Opinions recommendation of Targeting cardiac fibrosis with engineered T cells.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2022
Ablation of sphingosine kinase 2 suppresses fatty liver-associated hepatocellular carcinoma via downregulation of ceramide transfer protein
Oncogenesis·2022· 26 citedOpen Access
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Frequent Co-authors

Geoffrey W. McCaughan(31), Catherine A. Abbott(12), Denise Yu(10), Fiona M. Keane(7), Nicholas Shackel(6), Devanshi Seth(6), Paul Haber(6), Stephen M. Twigg(5), Peter H. McGuinness(5), Miriam Levy(4), Susan V. McLennan(4), Sumaiya Chowdhury(4), W. Bret Church(4), Katerina Ajami(4), Hui Zhang(4), Vanessa Gysbers(3), Tsun‐Wen Yao(3), Margaret G. Gall(3), Ana Júlia Vieira de Ribeiro(3), Thilo Kähne(3)