P. Brunel

Novartis (Switzerland) — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index1.2kcitations42works0.02yr avg
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Research Topics

Breast Cancer Treatment Studies(3), Head and Neck Cancer Studies(3), Reproductive System and Pregnancy(3), Synthesis of Organic Compounds(3), Glioma Diagnosis and Treatment(2)

Publications41 total

P2641Renal and cardiovascular benefits of treatment with angiotensin receptor blockers in patients with hypertension and chronic kidney disease: A systematic review and meta-analysis
European Heart Journal·2019
Data on synthesis, ADME and pharmacological properties and early safety pharmacology evaluation of a series of novel NURR1/NOT agonist potentially useful for the treatment of Parkinson's disease
Data in Brief·2019· 3 citedOpen Access
Development of a novel NURR1/NOT agonist from hit to lead and candidate for the potential treatment of Parkinson's disease
Bioorganic & Medicinal Chemistry Letters·2019· 16 citedOpen Access
SAR228810: an antibody for protofibrillar amyloid β peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA)
Alzheimer s Research & Therapy·2018· 42 citedOpen Access
P1656Large number of real world evidence studies confirmed effectiveness and safety in treatment with Val/Aml and Val/Aml/HCT worldwide across various ethical groups, disease severities and co-morbidities
European Heart Journal·2017Open Access
Is a reduction in albuminuria associated with renal and cardiovascular protection? A <i>post hoc</i> analysis of the <scp>ALTITUDE</scp> trial
Diabetes Obesity and Metabolism·2015· 55 cited
Spontaneous Metritis Related to the Presence of Vaginal Septum in Pregnant Sprague Dawley Crl:CD(SD) Rats
Veterinary Pathology·2010· 13 cited
P11: Spontaneous metritis related to the presence of vaginal septum in pregnant Sprague Dawley rats (CRL:CD(SD)): Impacts on reproductive toxicology studies
Experimental and Toxicologic Pathology·2009
Phase II Study of Paclitaxel Combined With Vinorelbine in Patients With Advanced Breast Cancer
American Journal of Clinical Oncology·2004· 8 cited
In vitro and in vivo characterization of TC‐1827, a novel brain <i>α</i><sub>4</sub><i>β</i><sub>2</sub> nicotinic receptor agonist with pro‐cognitive activity
Drug Development Research·2004· 17 cited
Different embryo‐fetal toxicity effects for three VLA‐4 antagonists
Birth Defects Research Part B Developmental and Reproductive Toxicology·2004· 15 cited
Critical period for a teratogenic VLA‐4 antagonist: Developmental effects and comparison of embryo drug concentrations of teratogenic and non‐teratogenic VLA‐4 antagonists
Birth Defects Research Part B Developmental and Reproductive Toxicology·2004· 15 cited
ChemInform Abstract: Synthesis of Benzo[de]chromene Analogue of Efaroxan.
ChemInform·2001
Synthesis of Benzo[de]chromene Analogue of Efaroxan
Heterocycles·2001· 2 citedOpen Access
New Substituted 1-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)piperidin-4-yl Derivatives with α<sub>2</sub>-Adrenoceptor Antagonist Activity
Journal of Medicinal Chemistry·2000· 20 citedOpen Access
ChemInform Abstract: A New Efficient Synthesis of Efaroxan.
ChemInform·2000
A new efficient synthesis of efaroxan
Bioorganic & Medicinal Chemistry Letters·1999· 14 cited
Phase II study of paclitaxel (P) twice a week as a radiosensitizer, after paclitaxel-carboplatin (C) induction chemotherapy (IC) in stage IIId–IV head and neck carcinoma (HNC)
European Journal of Cancer·1999· 2 cited
Breast cancer in patients under 18 years. Report of an inflammatory case and review of the literature
The Breast·1996· 2 citedOpen Access
[Exacerbation of myasthenia gravis by pefloxacin].
PubMed·1995· 8 cited
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Frequent Co-authors

C Maulard(8), S. Delanian(8), F Baillet(8), M. Housset(6), C Rozec(6), Patrice Mayer(5), Thierry Imbert(5), A Bieder(5), Judith Huart(4), Stéphane Barbellion(4), Pascal Barnéoud(3), Véronique Taupin(3), L. Ucla(3), M. Housset(3), Yves Chrétien(2), B Dufour(2), Laurent Pradier(2), P Michel-Langlet(2), Dominique Lesuisse(2), André Malanda(2)