Lacramioara Bintu

Stanford University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index4.0kcitations68works5.22yr avg
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Research Topics

CRISPR and Genetic Engineering(26), Genomics and Chromatin Dynamics(25), RNA and protein synthesis mechanisms(24), Gene Regulatory Network Analysis(11), Epigenetics and DNA Methylation(9)

Publications68 total

Structural probing of RNA hairpins quantifies protein occupancy on RNA and links it to function in human cells
2026Open Access
Bifunctional transcriptional effector domains control gene expression pulses in an occupancy-dependent manner
2025Open Access
What do you most hope we will achieve with mammalian synthetic biology within the next decade?
Cell Systems·2025
High-throughput mapping of modular regulatory domains in human RNA-binding proteins
Cell Systems·2025· 1 cited
Reduced Cas9 transgene silencing by incorporation of intron sequences
Nature Communications·2025Open Access
High-throughput development and characterization of new functional nanobodies for gene regulation and epigenetic control in human cells
2025Open Access
High-throughput development and characterization of new functional nanobodies for gene regulation and epigenetic control in human cells
2025Open Access
Epigenetic editing: from concept to clinic
Nature Reviews Drug Discovery·2025· 7 cited
FAIR sharing of Chromatin Tracing datasets using the newly developed 4DN FISH Omics Format.
PubMed·2025
Machine-guided dual-objective protein engineering for deimmunization and therapeutic functions
Cell Systems·2025· 5 cited
Human Synthetic Biology and Programmable Gene Regulation Control
Annual Review of Genomics and Human Genetics·2025· 1 citedOpen Access
Machine-Guided Dual-Objective Protein Engineering for Deimmunization and Therapeutic Functions
2025· 1 citedOpen Access
Single-molecule states link transcription factor binding to gene expression
Nature·2024· 26 citedOpen Access
High-throughput development and characterization of new functional nanobodies for gene regulation and epigenetic control in human cells
2024· 1 citedOpen Access
Development of compact transcriptional effectors using high-throughput measurements in diverse contexts
Nature Biotechnology·2024· 33 citedOpen Access
Tunable, proteolytic dosage control of CRISPR-Cas systems enables precise gene therapy for dosage sensitive disorders
2024· 2 citedOpen Access
The H3.3K36M oncohistone disrupts the establishment of epigenetic memory through loss of DNA methylation
Molecular Cell·2024· 6 citedOpen Access
Prediction and design of transcriptional repressor domains with large-scale mutational scans and deep learning
2024· 1 citedOpen Access
High-throughput affinity measurements of direct interactions between activation domains and co-activators
2024· 15 citedOpen Access
High-throughput discovery of regulatory effector domains in human RNA-binding proteins
2024Open Access
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Frequent Co-authors

Josh Tycko(21), Michael C. Bassik(18), Connor Ludwig(14), Adi Mukund(12), Michaela M. Hinks(11), Kaitlyn Spees(11), Georgi K. Marinov(9), William J. Greenleaf(8), Abby R. Thurm(8), Nicole DelRosso(7), Mike V. Van(7), Peter Suzuki(7), Anshul Kundaje(7), Joydeb Sinha(7), Gaelen T. Hess(6), Aradhana(6), Taihei Fujimori(6), Carlos Bustamante(5), Cecelia Andrews(5), Julia M. Schaepe(4)