Sritama Nath

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index2.5kcitations31works2.72yr avg
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Research Topics

Glycosylation and Glycoproteins Research(16), Pancreatic and Hepatic Oncology Research(11), Cancer Cells and Metastasis(6), CAR-T cell therapy research(6), Acute Myeloid Leukemia Research(4)

Publications31 total

Ongoing phase 1/2 trial of the hematopoietic progenitor kinase 1 (HPK1) inhibitor NDI-101150 as monotherapy or in combination with pembrolizumab: Clinical safety and efficacy update in clear cell renal cell carcinoma (ccRCC).
Journal of Clinical Oncology·2025
Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Shows Rapid Primary Engraftment with CD33-Negative Hematopoiesis in Patients with High-Risk Acute Myeloid Leukemia (AML) and Avoids Hematopoietic Toxicity during Gemtuzumab Ozogamicin (GO) Maintenance Post-Hematopoietic Cell Transplant (HCT).
Transplantation and Cellular Therapy·2024· 6 cited
Trial in Progress: Phase 1/2 Study of Donor-Derived Anti-CD33 Chimeric Antigen Receptor Expressing T Cells (VCAR33) in Patients with Relapsed or Refractory Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Transplantation
Transplantation and Cellular Therapy·2024· 2 cited
Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Shows Rapid Primary Engraftment with CD33-Negative Hematopoiesis in Patients with High-Risk Acute Myeloid Leukemia (AML) and Avoids Hematopoietic Toxicity during Gemtuzumab Ozogamicin (GO) Maintenance Post-Hematopoietic Cell Transplant (HCT)
Blood·2023· 9 cited
Phase 1/2 Study of Donor-Derived Anti-CD33 Chimeric Antigen Receptor Expressing T Cells (VCAR33) in Patients with Relapsed or Refractory Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Transplantation
Blood·2023· 11 cited
P1396: CD33-DELETED HEMATOPOIETIC STEM AND PROGENITOR CELLS DISPLAY NORMAL ENGRAFTMENT AFTER HEMATOPOIETIC CELL TRANSPLANT (HCT) AND TOLERATE POST-HCT GEMTUZUMAB OZOGAMICIN (GO) WITHOUT CYTOPENIAS
HemaSphere·2023· 3 citedOpen Access
Trial in Progress: A First-in-Human Phase 1/2 Study of Hematopoietic Stem Cell Transplantation (HCT) with VOR33 (CD33-Deleted Allograft) Followed By Treatment with Gemtuzumab Ozogamicin (GO) in Patients with CD33+ Acute Myeloid Leukemia (AML) Who Are at High-Risk of Post-HCT Relapse
Blood·2022· 5 cited
Overexpression of MUC1 Induces Non-Canonical TGF-β Signaling in Pancreatic Ductal Adenocarcinoma
Frontiers in Cell and Developmental Biology·2022· 21 citedOpen Access
Repression of MUC1 Promotes Expansion and Suppressive Function of Myeloid-Derived Suppressor Cells in Pancreatic and Breast Cancer Murine Models
International Journal of Molecular Sciences·2021· 17 citedOpen Access
Tumor -Associated MUC1 Regulates TGF-β Signaling and Function in Pancreatic Ductal Adenocarcinoma
2020· 1 citedOpen Access
Indomethacin enhances anti-tumor efficacy of a MUC1 peptide vaccine against breast cancer in MUC1 transgenic mice
PLoS ONE·2019· 21 citedOpen Access
SMAD4-independent activation of TGF-β signaling by MUC1 in a human pancreatic cancer cell line
Oncotarget·2018· 28 citedOpen Access
Abstract 321: MUC1 regulates TGFβ function in pancreatic cancer
Cancer Research·2017
Three-dimensional culture systems in cancer research: Focus on tumor spheroid model
Pharmacology & Therapeutics·2016· 878 citedOpen Access
X-linked inhibitor of apoptosis protein mediates tumor cell resistance to antibody-dependent cellular cytotoxicity
Cell Death and Disease·2016· 51 citedOpen Access
Delivery of Synthetic mRNA Encoding FOXP3 Antigen into Dendritic Cells for Inflammatory Breast Cancer Immunotherapy
Methods in molecular biology·2016· 3 cited
Abstract 2054: In pancreatic cancer, MUC1 regulates function of TGF-β and thus enhances metastasis
Cancer Research·2015
Mucin 1 Regulates Cox-2 Gene in Pancreatic Cancer
Pancreas·2015· 41 citedOpen Access
Cross-regulation of Myc and miR-308 and its role in the regulation of cell proliferation and apoptosis
2015
MUC1: a multifaceted oncoprotein with a key role in cancer progression
Trends in Molecular Medicine·2014· 814 citedOpen Access
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Frequent Co-authors

Pinku Mukherjee(18), Lopamudra Das Roy(10), Priyanka Grover(9), Dahlia M. Besmer(6), Nirali N. Shah(6), John F. DiPersio(6), Divya Koura(6), Hyung C. Suh(6), Guenther Koehne(6), Shanti Rao(5), Mahnaz Sahraei(4), K. Daneshvar(4), Amritha Kidiyoor(4), Mohammad Ahmad(4), Jennifer M. Curry(4), Matthew Cooper(4), Léa Bernard(4), Roland B. Walter(4), Glen Raffel(4), Gayathri R. Devi(3)