Andrea L. Britain

University of South Alabama — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index252citations33works0.02yr avg
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Research Topics

Phosphodiesterase function and regulation(16), Receptor Mechanisms and Signaling(12), Nitric Oxide and Endothelin Effects(6), Immune Response and Inflammation(4), Optical Imaging and Spectroscopy Techniques(3)

Publications33 total

Design of multiplexed, live cell imaging experiments using excitation scan-based hyperspectral imaging microscopy
2025
309 Measurement of agonist-induced calcium and mechanical signals in human airway smooth muscle cells
Journal of Clinical and Translational Science·2023Open Access
Extracellular vesicle-induced cyclic AMP signaling
Cellular Signalling·2022· 6 citedOpen Access
Measurement of agonist-induced Ca2+ signals in human airway smooth muscle cells using excitation scan-based hyperspectral imaging and image analysis approaches
2022Open Access
Hyperspectral imaging and adaptive thresholding to identify agonist-induced cAMP signals in pulmonary microvascular endothelial cells
2022· 1 citedOpen Access
Measurement of 3-Dimensional cAMP Distributions in Living Cells using 4-Dimensional (x, y, z, and λ) Hyperspectral FRET Imaging and Analysis
Journal of Visualized Experiments·2020· 6 citedOpen Access
Measurement of 3-Dimensional cAMP Distributions in Living Cells using 4-Dimensional (x, y, z, and λ) Hyperspectral FRET Imaging and Analysis
Journal of Visualized Experiments·2020
High Speed Spectral Measurements of cAMP Signals
2020Open Access
PGE <sub>1</sub> Triggers Camp Signals Generated at the Plasma Membrane and at Intracellular Locations in Pulmonary Microvascular Endothelial Cells
2020
Kinetics of Agonist-Induced Calcium Signals in Human Airway Smooth Muscle Cells
2020
cAMP signaling primes lung endothelial cells to activate caspase-1 during <i>Pseudomonas aeruginosa</i> infection
American Journal of Physiology-Lung Cellular and Molecular Physiology·2020· 9 citedOpen Access
Excitation-Scanning Hyperspectral Imaging Microscopy to Efficiently Discriminate Fluorescence Signals
Journal of Visualized Experiments·2019· 4 cited
Excitation-Scanning Hyperspectral Imaging Microscopy to Efficiently Discriminate Fluorescence Signals
Journal of Visualized Experiments·2019· 13 citedOpen Access
Spectral imaging of FRET‐based sensors reveals sustained cAMP gradients in three spatial dimensions
Cytometry Part A·2018· 28 citedOpen Access
5D imaging approaches reveal the formation of distinct intracellular cAMP spatial gradients
Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE·2017Open Access
Real Time Tracking of cAMP Gradients and Changes in PKA Activity using Hyperspectral Imaging and Analysis Approaches
Biophysical Journal·2017Open Access
5 Dimensional Hyperspectral FRET Imaging and Analysis Approaches for Measuring cAMP Gradients
Biophysical Journal·2017Open Access
Real Time Four Dimensional Measurement of cAMP Gradients in Pulmonary Microvascular Endothelial Cells
The FASEB Journal·2016
A Mathematical Model of Calcium and cAMP Signaling in Pulmonary Microvascular Endothelial Cells
The FASEB Journal·2016
Hyperspectral Imaging Approaches for Measuring Three‐Dimensional FRET
The FASEB Journal·2016
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Frequent Co-authors

Thomas C. Rich(30), Silas J. Leavesley(23), Naga S. Annamdevula(19), Rachel Sweat(7), John Griswold(6), Joshua Deal(6), Kenny T. Trinh(4), Karla A. McInnis(3), John E. Oakes(3), Chase Hoffman(3), Savannah J. West(3), Bing Zhu(3), Samuel A. Mayes(3), Santina Johnson(3), Michael Francis(3), Deepak A. Deshpande(3), K. Adam Morrow(2), Roland Seifert(2), Dara W. Frank(2), Troy Stevens(2)