Rosemarie Tomlinson

Eli Lilly (United Kingdom) — United Kingdom

Neuroscience · Life Sciences

8h-index872citations13works0.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(8), Ion channel regulation and function(3), Molecular Sensors and Ion Detection(3), Neurotransmitter Receptor Influence on Behavior(2), Receptor Mechanisms and Signaling(2)

Publications13 total

Naphthyl piperazines with dual activity as 5-HT1D antagonists and 5-HT reuptake inhibitors
Bioorganic & Medicinal Chemistry Letters·2007· 7 citedOpen Access
Novel selective and potent 5-HT reuptake inhibitors with 5-HT1D antagonist activity: chemistry and pharmacological evaluation of a series of thienopyran derivatives
Bioorganic & Medicinal Chemistry·2004· 16 cited
Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment
Neuroscience·2004· 249 cited
Inhibition of group I metabotropic glutamate receptor responses in vivo in rats by a new generation of carboxyphenylglycine-like amino acid antagonists
Neuroscience Letters·2002· 35 cited
In vitro activity of LY393558, an inhibitor of the 5-hydroxytryptamine transporter with 5-HT1B/1D/2 receptor antagonist properties
European Journal of Pharmacology·2001· 13 cited
Synthesis, Pharmacological Characterization, and Molecular Modeling of Heterobicyclic Amino Acids Related to (+)-2-Aminobicyclo[3.1.0]hexane- 2,6-dicarboxylic Acid (LY354740):  Identification of Two New Potent, Selective, and Systemically Active Agonists for Group II Metabotropic Glutamate Receptors
Journal of Medicinal Chemistry·1999· 286 citedOpen Access
ChemInform Abstract: 2,3′‐Disubstituted‐2‐(2′‐carboxycyclopropyl)glycines as Potent and Selective Antagonists of Metabotropic Glutamate Receptors.
ChemInform·1999
ChemInform Abstract: Synthesis and Metabotropic Glutamate Receptor Antagonist Activity of N<sup>1</sup>‐Substituted Analogues of 2R,4R‐4‐Aminopyrrolidine‐2,4‐dicarboxylic Acid.
ChemInform·1998
Synthesis and metabotropic glutamate receptor antagonist activity of N1-substituted analogs of 2R,4R-4-aminopyrrolidine-2,4-dicarboxylic acid
Bioorganic & Medicinal Chemistry Letters·1998· 15 citedOpen Access
Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines
Neuropharmacology·1998· 41 cited
Anthraquinones related to rhein inhibit glucose uptake into chondrocytes. A mechanism for anti-osteoarthritis drugs?
Bioorganic & Medicinal Chemistry Letters·1997· 4 cited
Agonist and antagonist pharmacology of cloned human group 1 mGluRs
Neuropharmacology·1996
Relationship between inhibition of prostaglandin synthesis and drug efficacy: Support for the current theory on mode of action of aspirin-like drugs
Biochemical and Biophysical Research Communications·1972· 206 cited

Frequent Co-authors

Ann E. Kingston(8), Rebecca A. Wright(5), Bryan G. Johnson(5), Matthew J. Valli(3), Darryle D. Schoepp(3), Stephen Carney(3), John R. Boot(3), Richard J. Broadmore(3), James A. Monn(2), Joseph P. Tizzano(2), J. Paul Burnett(2), Nancy G. Mayne(2), David Lodge(2), Barry P. Clark(2), Jeremy Gilmore(2), Jeremy Findlay(2), Lorna Hayhurst(2), Louise Wallace(2), Steven M. Massey(1), Marvin M. Hansen(1)