Tao Zu

University of Florida — United States

Neuroscience · Life Sciences

22h-index4.8kcitations31works2.02yr avg
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Research Topics

Genetic Neurodegenerative Diseases(20), Mitochondrial Function and Pathology(11), Amyotrophic Lateral Sclerosis Research(11), RNA Research and Splicing(9), Neurogenetic and Muscular Disorders Research(5)

Publications31 total

Repeat-associated non-AUG translation as a common mechanism for the polyGln ataxias
Cell Reports·2025Open Access
Repeat associated non-AUG translation as a common mechanism for the polyGln ataxias
2025Open Access
<i>CASP8</i> intronic expansion identified by poly-glycine-arginine pathology increases Alzheimer’s disease risk
Proceedings of the National Academy of Sciences·2025· 6 citedOpen Access
Staufen Impairs Autophagy in Neurodegeneration
Annals of Neurology·2022· 25 citedOpen Access
CCG•CGG interruptions in high‐penetrance SCA8 families increase RAN translation and protein toxicity
EMBO Molecular Medicine·2021· 33 citedOpen Access
The alternative initiation factor eIF2A plays key role in RAN translation of myotonic dystrophy type 2 CCUG•CAGG repeats
Human Molecular Genetics·2021· 31 citedOpen Access
Repeat length increases disease penetrance and severity in <i>C9orf72</i> ALS/FTD BAC transgenic mice
Human Molecular Genetics·2020· 16 citedOpen Access
Survival and Motor Phenotypes in FVB C9-500 ALS/FTD BAC Transgenic Mice Reproduced by Multiple Labs
Neuron·2020· 42 citedOpen Access
Metformin inhibits RAN translation through PKR pathway and mitigates disease in <i>C9orf72</i> ALS/FTD mice
Proceedings of the National Academy of Sciences·2020· 138 citedOpen Access
Repeat length increases disease penetrance and severity in <i>C9orf72</i> ALS/FTD BAC transgenic mice
2020· 1 citedOpen Access
Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model
Neuron·2019· 107 citedOpen Access
Staufen blocks autophagy in neurodegeneration
2019· 6 citedOpen Access
Targeting RAN proteins improves phenotypes in C9orf72 BAC ALS/FTD mice
2019
<scp>SCA</scp> 8 <scp>RAN</scp> polySer protein preferentially accumulates in white matter regions and is regulated by <scp>eIF</scp> 3F
The EMBO Journal·2018· 78 citedOpen Access
Repeat-Associated Non-ATG Translation in Neurological Diseases
Cold Spring Harbor Perspectives in Biology·2018· 42 citedOpen Access
RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2
Neuron·2017· 146 citedOpen Access
C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD
Neuron·2016· 371 citedOpen Access
RAN Translation in Huntington Disease
Neuron·2015· 340 citedOpen Access
Mutant  -III Spectrin Causes mGluR1  Mislocalization and Functional Deficits in a Mouse Model of Spinocerebellar Ataxia Type 5
Journal of Neuroscience·2014· 81 citedOpen Access
Hippocampal sclerosis dementia with the C9ORF72 hexanucleotide repeat expansion
Neurobiology of Aging·2014· 36 citedOpen Access
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Frequent Co-authors

Laura P.W. Ranum(22), Mónica Báñez-Coronel(9), H. Brent Clark(8), Anthony T. Yachnis(7), Harry T. Orr(7), Shu Guo(7), Lien Nguyen(7), Juan C. Troncoso(6), Amrutha Pattamatta(6), Tammy Reid(5), S. H. Subramony(5), Tetsuo Ashizawa(5), Lauren A. Laboissonniere(5), Olga Pletniková(4), Olgert Bardhi(4), Solaleh Khoramian Tusi(4), Lisa Duvick(4), Huda Y. Zoghbi(4), Eric T. Wang(4), Yuanjing Liu(3)