Amr Sonousi

Cairo University — Egypt

Chemistry · Physical Sciences

14h-index560citations35works5.62yr avg
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Research Topics

Synthesis and biological activity(12), RNA and protein synthesis mechanisms(6), Cancer therapeutics and mechanisms(6), Carbohydrate Chemistry and Synthesis(4), Computational Drug Discovery Methods(3)

Publications35 total

Author response for "New multitarget antidiabetic potential agents based on sulfaguanidine: Design, synthesis, and biological evaluation"
2026
New multitarget antidiabetic potential agents based on sulfaguanidine: design, synthesis, and biological evaluation
RSC Advances·2026Open Access
Design, Synthesis, Biological Evaluation, and In Silico Studies of Novel Furo[2,3‐ <i>d</i> ]pyrimidine Derivatives as EGFR Inhibitors With Potential Antitumor Activity
Archiv der Pharmazie·2025
Thieno[2,3-d]pyrimidine derivatives as topoisomerase II inhibitors: design, synthesis, anticancer evaluation, and in silico studies
Bioorganic Chemistry·2025· 3 cited
Design, Synthesis, Molecular Docking, and Biological Evaluation of Novel 1,2,4-Oxadiazole-Based Derivatives as Inhibitors of Trypsin, ALDH2, and iNOS
Russian Journal of Bioorganic Chemistry·2025
Novel Ag(I) and Zn(II) complexes based on benzenesulfonamide ligand: Synthesis, characterization, and biological evaluation as multitarget antidiabetic agents
Inorganica Chimica Acta·2025
Impact of trifluoromethyl Ugi adducts as anticancer agents: EGFR inhibition, apoptosis induction and miRNA up-regulation
RSC Advances·2025· 1 citedOpen Access
Combating oxi-inflamm-aging: Passerini adducts tethered with 1,2,3-triazoles for enhanced antioxidant defense and 5-LOX inhibition
RSC Medicinal Chemistry·2025· 1 citedOpen Access
Design, synthesis, and cytotoxicity screening of novel pyrazolopyrimidines over renal cell carcinoma (UO-31 cells) as p38α inhibitors, and apoptotic cells inducing activities
European Journal of Medicinal Chemistry·2024· 8 cited
Author response for "Design, synthesis, and biological evaluation of novel thiazole derivatives as PI3K/mTOR dual inhibitors"
2024
New 1,2,4-oxadiazole derivatives as potential multifunctional agents for the treatment of Alzheimer’s disease: design, synthesis, and biological evaluation
BMC Chemistry·2024· 14 citedOpen Access
Design, synthesis, and biological evaluation of novel thiazole derivatives as PI3K/mTOR dual inhibitors
RSC Medicinal Chemistry·2024· 13 citedOpen Access
Novel sulfonamide derivatives as multitarget antidiabetic agents: design, synthesis, and biological evaluation
RSC Advances·2024· 26 citedOpen Access
Design, synthesis, and biological evaluation of 1,2,4-oxadiazole-based derivatives as multitarget anti-Alzheimer agents
RSC Medicinal Chemistry·2024· 13 citedOpen Access
Novel sofosbuvir derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective
Scientific Reports·2023· 4 citedOpen Access
Design, synthesis, anticancer, and antibacterial evaluation of some quinazolinone‐based derivatives as DHFR inhibitors
Drug Development Research·2023· 28 citedOpen Access
New trends in synthetic drugs and natural products targeting 20S proteasomes in cancers
Bioorganic Chemistry·2023· 66 cited
Design and synthesis of novel quinazolinone-based derivatives as EGFR inhibitors with antitumor activity
Journal of Enzyme Inhibition and Medicinal Chemistry·2022· 33 citedOpen Access
Structure‐Activity Relationships for 5′′ Modifications of 4,5‐Aminoglycoside Antibiotics
ChemMedChem·2022· 16 citedOpen Access
Design, synthesis and evaluation of anticancer activity of new pyrazoline derivatives by down-regulation of VEGF: Molecular docking and apoptosis inducing activity
Bioorganic Chemistry·2021· 40 cited
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Frequent Co-authors

Rasha A. Hassan(9), David Crich(9), Mohammed Salah Ayoup(8), Asmaa E. Kassab(8), Amr M. Abdou(7), Andrea Vasella(6), Doaa A. Ghareeb(6), Soha H. Emam(5), Erik C. Böttger(5), Hamida Abdel‐Hamid(5), Samah Ashraf(4), Eman O. Osman(3), Jonathan C.K. Quirke(3), Marina Gysin(3), Klara Haldimann(3), Sven N. Hobbie(3), Jochen Schacht(3), Aliaa A. Masoud(3), Samar I. Faggal(3), Yara El‐Dash(3)