Yvette Hooks

Wellcome Sanger Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index5.0kcitations52works4.32yr avg
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Research Topics

Cancer Genomics and Diagnostics(24), Genetic factors in colorectal cancer(11), Single-cell and spatial transcriptomics(8), Renal cell carcinoma treatment(5), Evolution and Genetic Dynamics(5)

Publications51 total

The earliest stages of neoplastic transformation in Familial Adenomatous Polyposis
2025Open Access
The somatic mutation landscape of normal gastric epithelium
Nature·2025· 23 citedOpen Access
Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency
Nature Genetics·2025· 5 citedOpen Access
Cancer-independent somatic mutation of the wild-type NF1 allele in normal tissues in neurofibromatosis type 1
Nature Genetics·2025· 5 citedOpen Access
Multifocal, multiphenotypic tumours arising from an MTOR mutation acquired in early embryogenesis
Oncogene·2024· 3 citedOpen Access
Letter: Cancer-independent, second somatic <i>NF1</i> mutation of normal tissues in neurofibromatosis type 1
2024Open Access
Convergent evolution of somatic escape variants in <i>SERPINA1</i> in the liver in alpha-1 anti-trypsin deficiency
2024· 1 citedOpen Access
1O The somatic mutation landscape of the normal and malignant pancreas
Annals of Oncology·2024Open Access
The somatic mutation landscape of normal gastric epithelium
2024· 2 citedOpen Access
Multifocal, multiphenotypic tumours arising from an MTOR mutation acquired in early embryogenesis
2023Open Access
Somatic mutation rates scale with lifespan across mammals
Yearbook of pediatric endocrinology·2023
Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer
Cancer Cell·2022· 223 citedOpen Access
The mutational landscape of human somatic and germline cells
Yearbook of pediatric endocrinology·2022· 13 cited
Clonal diversification and histogenesis of malignant germ cell tumours
Nature Communications·2022· 17 citedOpen Access
Somatic mutation rates scale with lifespan across mammals
Nature·2022· 436 citedOpen Access
Clonal diversification and histogenesis of malignant germ cell tumours
2022· 3 citedOpen Access
Mapping Single Cell Transcriptomes in the Intra-Tumoural and Associated Territories of Kidney Cancer
SSRN Electronic Journal·2022· 1 citedOpen Access
Multi-regional characterisation of renal cell carcinoma and microenvironment at single cell resolution
2021· 3 citedOpen Access
Convergent somatic mutations in metabolism genes in chronic liver disease
Nature·2021· 182 citedOpen Access
The mutational landscape of human somatic and germline cells
Nature·2021· 354 cited
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Frequent Co-authors

Peter J. Campbell(35), Tim Coorens(30), Iñigo Martincorena(26), Michael R. Stratton(25), Timothy Butler(22), Luiza Moore(19), Mathijs A. Sanders(19), Thomas J. Mitchell(15), Raheleh Rahbari(12), Henry Lee-Six(12), Alex Cagan(12), Thomas R. W. Oliver(12), Anne Y. Warren(12), Andrew Lawson(11), Philip S. Robinson(11), Daniel Leongamornlert(10), Sam Behjati(10), Hyunchul Jung(10), Kourosh Saeb‐Parsy(9), Rashesh Sanghvi(9)