Yilai Shu

Zhejiang Chinese Medical University — China

Neuroscience · Life Sciences

38h-index6.4kcitations154works16.22yr avg
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Research Topics

Hearing, Cochlea, Tinnitus, Genetics(68), RNA regulation and disease(42), CRISPR and Genetic Engineering(37), Hearing Loss and Rehabilitation(26), Vestibular and auditory disorders(18)

Publications153 total

International expert consensus on gene therapy for hereditary hearing loss: Based on clinical trials
Med·2025Open Access
Unraveling the genetic basis of post-infancy diagnosed sensorineural hearing loss using whole exome sequencing
Hearing Research·2025
Unlocking mRNA-driven CRISPR-Cas9 gene therapy via optimizing mRNA and the delivery vectors
Molecular Therapy — Nucleic Acids·2025Open Access
Comparative analysis of RNA versus protein splicing in dual AAV-mediated gene therapy in a mouse model of DFNB9 deafness
Molecular Therapy·2025Open Access
P3.12.31 Rezivertinib in Advanced NSCLC Patients With EGFR T790M Mutation via Tissue/Plasma Samples: Pooled Analysis of 2 Clinical Studies
Journal of Thoracic Oncology·2025
Treating Hearing Loss: From Cochlear Implantation to Gene Therapy
Advanced Science·2025· 2 citedOpen Access
Clinical gene therapy restores hearing: a paradigm shift
Trends in Molecular Medicine·2025· 1 cited
Prevalence and spectrum of STRC variants in 1015 sensorineural hearing loss patients: insights from the Chinese population
Molecular Genetics and Genomics·2025· 1 cited
Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and nonhuman primates
Molecular Therapy — Methods & Clinical Development·2025Open Access
Hearing restoration by gene replacement therapy for a multisite-expressed gene in a mouse model of human DFNB111 deafness
The American Journal of Human Genetics·2025· 1 citedOpen Access
Single-dose genome editing therapy rescues auditory and vestibular functions in adult mice with DFNA41 deafness
Journal of Clinical Investigation·2025· 1 citedOpen Access
PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation
Nature Communications·2025· 4 citedOpen Access
Gene Therapy vs Cochlear Implantation in Restoring Hearing Function and Speech Perception for Individuals With Congenital Deafness
JAMA Neurology·2025· 8 citedOpen Access
Viral and non-viral vectors in gene therapy: current state and clinical perspectives
EBioMedicine·2025· 29 citedOpen Access
Molecular Determinants of TMC Protein Biogenesis and Trafficking
International Journal of Molecular Sciences·2025Open Access
In Vitro and Animal Studies of Human Natural Killer Cell-Derived Exosomes for the Treatment of Otitis Media
Neuroscience Bulletin·2025Open Access
Audiological characteristics following gene therapy in patients with autosomal recessive deafness 9
Med·2025· 7 citedOpen Access
Leonurine protects against cisplatin-induced ototoxicity through its anti-oxidation and anti-apoptosis properties
Toxicology Letters·2025· 3 cited
The impact of high-frequency rTMS treatment on brain activity in PSCI patients: a TMS-EEG study
Frontiers in Neurology·2025· 3 citedOpen Access
Preliminary evidence for enhanced auditory cortex activation and mental development after gene therapy in children with autosomal recessive deafness 9
Nature Human Behaviour·2025· 5 cited
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Frequent Co-authors

Zheng‐Yi Chen(15), Huawei Li(13), Daqi Wang(12), Bing Chen(9), Yuxin Chen(8), Renjie Chai(8), Yong Tao(7), Chong Cui(7), Geng‐Lin Li(7), Jinghan Wang(6), Mingqian Huang(5), Weijia Kong(5), Xiaoting Cheng(5), Honghai Tang(5), Zhijiao Xu(5), David B. Thompson(4), David R. Liu(4), Longlong Zhang(4), Luo Guo(4), Wuqing Wang(4)