Frederick Arce

University College London — United Kingdom

Immunology and Microbiology · Life Sciences

16h-index2.7kcitations32works0.02yr avg
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Research Topics

Immunotherapy and Immune Responses(13), Virus-based gene therapy research(9), RNA Interference and Gene Delivery(5), Immune Cell Function and Interaction(5), Cancer Immunotherapy and Biomarkers(4)

Publications32 total

Abstract A127: Innate crosstalk between ILC and interstitial macrophages promotes lung cancer regression in response to IL-12 therapy
Cancer Immunology Research·2016
Genetically Engineering HBV-Specific CD8+ T Cells Resistant to Trail-Mediated Apoptosis
Journal of Hepatology·2016
Innate crosstalk between ILC and interstitial macrophages promotes lung cancer regression in response to IL-12 therapy
UCL Discovery (University College London)·2016
GENETICALLY ENGINEERING HBV-SPECIFIC CD8+T CELLS RESISTANT TO TRAIL-MEDIATED APOPTOSIS
UCL Discovery (University College London)·2015
A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice
Oncotarget·2014· 67 citedOpen Access
Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1
Cell Death and Differentiation·2013· 118 citedOpen Access
Assessing T-cell responses in anticancer immunotherapy
OncoImmunology·2013· 27 citedOpen Access
Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti–CTLA-4 therapy against melanoma
The Journal of Experimental Medicine·2013· 1.4k citedOpen Access
Harnessing alveolar macrophages for sustained mucosal T-cell recall confers long-term protection to mice against lethal influenza challenge without clinical disease
Mucosal Immunology·2013· 22 citedOpen Access
Immune modulation by genetic modification of dendritic cells with lentiviral vectors
Virus Research·2013· 20 cited
Lentiviral Vectors in Immunotherapy
InTech eBooks·2013· 2 citedOpen Access
Her1 vaccine for epithelial tumors therapy: primeboosting strategy based on lentiviral-protein vaccination to potentiate the vaccine effect
2012
Lentiviral vector followed by protein immunisation breaks tolerance against the self‐antigen Her1 and results in lung cancer immunotherapy
The Journal of Gene Medicine·2012· 5 cited
PD-L1 co-stimulation, ligand-induced TCR down-modulation and anti-tumor immunotherapy
OncoImmunology·2012· 46 citedOpen Access
Lentiviral Vectors and Gene Therapy
SpringerBriefs in biochemistry and molecular biology·2012· 4 cited
Immunomodulation by Genetic Modification Using Lentiviral Vectors
SpringerBriefs in biochemistry and molecular biology·2012
Selective Activation of Intracellular Signalling Pathways in Dendritic Cells for Cancer Immunotherapy
Anti-Cancer Agents in Medicinal Chemistry·2012· 26 cited
Targeting lentiviral vectors for cancer immunotherapy. Arce F, Breckpot K, Collins M, Escors D.Curr Cancer Ther Rev. 2011 Nov;7(4):248-260.
VUBIR (Vrije Universiteit Brussel)·2011
Targeting Lentiviral Vectors for Cancer Immunotherapy
Current Cancer Therapy Reviews·2011· 18 cited
PD‐L1 co‐stimulation contributes to ligand‐induced T cell receptor down‐modulation on CD8 <sup>+</sup> T cells
EMBO Molecular Medicine·2011· 265 citedOpen Access
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Frequent Co-authors

David Escors(20), Karine Breckpot(14), Mary Collins(9), Katarzyna Karwacz(8), Grazyna Kochan(8), Holly Stephenson(5), Christopher Bricogne(4), Thérèse Liechtenstein(4), Benny Chain(3), Noemí Pérez‐Janices(3), Idoia Blanco‐Luquin(3), David Guerrero‐Setas(3), Inès Dufait(3), Alessio Lanna(3), Mala K. Maini(3), Jake Y. Henry(2), Karl S. Peggs(2), Sergio A. Quezada(2), Douglas MacDonald(2), Michael R. Ehrenstein(2)