Nobutaka Kato

Broad Institute — United States

Medicine · Health Sciences

25h-index3.3kcitations42works0.02yr avg
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Research Topics

Malaria Research and Control(20), Computational Drug Discovery Methods(10), HIV/AIDS drug development and treatment(8), Mosquito-borne diseases and control(7), Synthesis and Catalytic Reactions(5)

Publications42 total

Author Correction: Diversity-oriented synthesis yields novel multistage antimalarial inhibitors
Nature·2025Open Access
Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review 38
British Journal of Pharmacology·2023· 13 citedOpen Access
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target
Science Translational Medicine·2023· 26 citedOpen Access
MalDA, Accelerating Malaria Drug Discovery
Trends in Parasitology·2021· 114 citedOpen Access
Orthosteric–allosteric dual inhibitors of PfHT1 as selective antimalarial agents
Proceedings of the National Academy of Sciences·2021· 32 citedOpen Access
Bicyclic azetidines kill the diarrheal pathogen <i>Cryptosporidium</i> in mice by inhibiting parasite phenylalanyl-tRNA synthetase
Science Translational Medicine·2020· 75 citedOpen Access
Structural Basis for Blocking Sugar Uptake into the Malaria Parasite Plasmodium falciparum
Cell·2020· 71 cited
Orthosteric-allosteric dual inhibitors of PfHT1 as selective anti-malarial agents
2020· 2 citedOpen Access
Natural product-inspired aryl isonitriles as a new class of antimalarial compounds against drug-resistant parasites
Bioorganic & Medicinal Chemistry·2020· 6 citedOpen Access
Rapid and Systematic Exploration of Chemical Space Relevant to Artemisinins: Anti-malarial Activities of Skeletally Diversified Tetracyclic Peroxides and 6-Aza-artemisinins
The Journal of Organic Chemistry·2020· 13 cited
Modular, stereocontrolled C <sub>β</sub> –H/C <sub>α</sub> –C activation of alkyl carboxylic acids
Proceedings of the National Academy of Sciences·2019· 52 citedOpen Access
Modular, Stereocontrolled Cβ–H/Cα–C Activation of Alkyl Carboxylic Acids
2019Open Access
Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection
PLoS Pathogens·2018· 94 citedOpen Access
Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity
Antimicrobial Agents and Chemotherapy·2018· 48 citedOpen Access
Phenotypic Screening of Small Molecules with Antimalarial Activity for Three Different Parasitic Life Stages
Methods in molecular biology·2018· 4 citedOpen Access
Synthesis of a Bicyclic Azetidine with In Vivo Antimalarial Activity Enabled by Stereospecific, Directed C(sp<sup>3</sup>)–H Arylation
Journal of the American Chemical Society·2017· 140 citedOpen Access
Discovery of Antimalarial Azetidine-2-carbonitriles That Inhibit <i>P. falciparum</i> Dihydroorotate Dehydrogenase
ACS Medicinal Chemistry Letters·2017· 53 citedOpen Access
CCDC 1543941: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
CCDC 1543940: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors
Nature·2016· 261 citedOpen Access
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Frequent Co-authors

Elizabeth A. Winzeler(13), Stuart L. Schreiber(13), Case W. McNamara(11), Eamon Comer(10), Micah Maetani(8), Christina Scherer(8), David Plouffe(7), Tomoyo Sakata‐Kato(7), Emily R. Derbyshire(7), Anne‐Marie Zeeman(6), Kerstin Gagaring(6), Clemens H. M. Kocken(6), Bruno Melillo(6), Kelli Kuhen(5), A. S. Nagle(5), Arnab K. Chatterjee(5), Lee M(5), Koen J. Dechering(5), Stephan Meister(5), David A. Fidock(5)