Gioacchino Natoli

Istituti di Ricovero e Cura a Carattere Scientifico — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

77h-index33.8kcitations238works8.12yr avg
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Research Topics

Epigenetics and DNA Methylation(40), Immune Response and Inflammation(39), NF-κB Signaling Pathways(34), Immune cells in cancer(33), Hepatitis B Virus Studies(28)

Publications238 total

FCRL3 is an immunoregulatory receptor that restrains the activation of human memory T lymphocytes
The Journal of Experimental Medicine·2025· 1 citedOpen Access
Control of myeloid lineage fidelity and response to stimuli by ISWI-enforced nucleosome phasing
Immunity·2025
FCRL3 is an immunoregulatory receptor that restrains the activation of human memory T lymphocytes
immuneACCESS·2025
CellHit: a web server to predict and analyze cancer patients’ drug responsiveness
Nucleic Acids Research·2025· 1 citedOpen Access
Learning and actioning general principles of cancer cell drug sensitivity
Nature Communications·2025· 18 citedOpen Access
A framework to mine laser microdissection-based omics data and uncover regulators of pancreatic cancer heterogeneity
GigaScience·2025· 1 citedOpen Access
Mapping functional to morphological variation reveals the basis of regional extracellular matrix subversion and nerve invasion in pancreatic cancer
Pancreatology·2024· 1 cited
Leveraging the tug-of-war with genomic retroelements to enhance immunotherapy of pancreatic cancer
Gut·2024
WNT Oncogenic Transcription Requires MYC Suppression of Lysosomal Activity and EPCAM Stabilization in Gastric Tumors
Gastroenterology·2024· 8 citedOpen Access
An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors
Molecular Systems Biology·2024· 2 citedOpen Access
The landscape of cancer-rewired GPCR signaling axes
Cell Genomics·2024· 20 citedOpen Access
Learning and actioning general principles of cancer cell drug sensitivity
2024· 1 citedOpen Access
Activation of endogenous retroviruses and induction of viral mimicry by MEK1/2 inhibition in pancreatic cancer
Science Advances·2024· 21 citedOpen Access
Mapping functional to morphological variation reveals the basis of regional extracellular matrix subversion and nerve invasion in pancreatic cancer
Cancer Cell·2024· 57 cited
Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide
Molecular Cell·2024· 15 citedOpen Access
Abstract A092: <i>Exploiting the neural-like properties of a new pancreatic cancer morpho-biotype for the development of a combinatorial treatment targeting tumor heterogeneity</i>
Cancer Research·2024
High-sensitivity analysis of clonal hematopoiesis reveals increased clonal complexity of potential-driver mutations in severe COVID-19 patients
PLoS ONE·2024Open Access
The study of spatial relationship between Restrictor complex and RNA-Pol II through Expansion Microscopy
BIO Web of Conferences·2024Open Access
Cancer Evolution: A Multifaceted Affair
Cancer Discovery·2023· 66 citedOpen Access
Restrictor synergizes with Symplekin and PNUTS to terminate extragenic transcription
Genes & Development·2023· 23 citedOpen Access
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Frequent Co-authors

Simona Saccani(9), Iros Barozzi(8), Serena Ghisletti(8), Massimo Levrero(7), Francesca De Santa(5), Elena Prosperini(5), Clara Balsano(5), Renato Ostuni(4), Paolo Chirillo(4), Alberto Mantovani(3), Pankaj Kapahi(3), Takayuki Takahashi(3), Samuele Notarbartolo(3), Giuseppe Testa(3), Flore Mietton(3), Sara Polletti(3), Chia‐Lin Wei(3), Serafino Pantano(3), Antonio Costanzo(3), Angelo Ianni(3)